Type of Publication: | Contribution to a conference collection |
URI (citable link): | http://nbn-resolving.de/urn:nbn:de:bsz:352-177364 |
Author: | Strauch, Martin; Galizia, Giovanni |
Year of publication: | 2011 |
Conference: | The ACM fifth international workshop on Data and text mining in biomedical informatics - DTMBIO '11, Oct 24, 2011 - Oct 24, 2011, Glasgow, Scotland, UK |
Published in: | Proceedings of the ACM fifth international workshop on Data and text mining in biomedical informatics - DTMBIO '11. - New York, New York, USA : ACM Press, 2011. - pp. 3-10. - ISBN 978-1-4503-0960-8 |
DOI (citable link): | https://dx.doi.org/10.1145/2064696.2064700 |
Summary: |
The calcium-imaging technique allows us to record movies of brain activity in the antennal lobe of the fruitfly Drosophila melanogaster, a brain compartment where information about odors is processed. For signal processing that scales up with the growing data sizes in imaging, we have developed an approximate Principal Component Analysis (PCA) for fast dimensionality reduction. The approach relies on selecting a set of relevant pixels from the movies based on a priori knowledge about the nature of the data, ensuring a highquality approximation. Once in PCA space, we can efficiently perform source separation, e.g to detect biological signals in the movies and to remove artifacts.
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Subject (DDC): | 570 Biosciences, Biology |
Keywords: | Biological image mining, approximate PCA, Monte Carlo algorithm, source separation |
Link to License: | In Copyright |
Bibliography of Konstanz: | Yes |
STRAUCH, Martin, Giovanni GALIZIA, 2011. Fast PCA for processing Calcium-imaging data from the brain of Drosophila melanogaster. The ACM fifth international workshop on Data and text mining in biomedical informatics - DTMBIO '11. Glasgow, Scotland, UK, Oct 24, 2011 - Oct 24, 2011. In: Proceedings of the ACM fifth international workshop on Data and text mining in biomedical informatics - DTMBIO '11. New York, New York, USA:ACM Press, pp. 3-10. ISBN 978-1-4503-0960-8. Available under: doi: 10.1145/2064696.2064700
@inproceedings{Strauch2011proce-17736, title={Fast PCA for processing Calcium-imaging data from the brain of Drosophila melanogaster}, year={2011}, doi={10.1145/2064696.2064700}, isbn={978-1-4503-0960-8}, address={New York, New York, USA}, publisher={ACM Press}, booktitle={Proceedings of the ACM fifth international workshop on Data and text mining in biomedical informatics - DTMBIO '11}, pages={3--10}, author={Strauch, Martin and Galizia, Giovanni} }
Galizia.pdf | 198 |