Evolving thermostable reverse transcriptase activity in a DNA polymerase scaffold
| Publikationstyp: | Zeitschriftenartikel |
| URI (zitierfähiger Link): | http://nbn-resolving.de/urn:nbn:de:bsz:352-167259 |
| Autor/innen: | Sauter, Katharina B.; Marx, Andreas |
| Erscheinungsjahr: | 2006 |
| Erschienen in: | Angewandte Chemie International Edition ; 45 (2006), 45. - S. 7633-7635. - ISSN 1433-7851 |
| Pubmed ID: | 17054304 |
| DOI (zitierfähiger Link): | https://dx.doi.org/10.1002/anie.200602772 |
| Zusammenfassung: |
Thermostable DNA polymerases normally exhibit no significant intrinsic activities to reverse transcribe RNA into DNA. We show that enzymes with significantly increased reverse transcription ability can be generated by directed evolution.
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| Fachgebiet (DDC): | 540 Chemie |
| Schlagwörter: | directed evolution, DNA polymerase, DNA recognition, polymerase chain reaction, reverse transcriptase |
| Link zur Lizenz: | Deposit-Lizenz |
| Universitätsbibliographie: | Ja |
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SAUTER, Katharina B., Andreas MARX, 2006. Evolving thermostable reverse transcriptase activity in a DNA polymerase scaffold. In: Angewandte Chemie International Edition. 45(45), pp. 7633-7635. ISSN 1433-7851
@article{Sauter2006-11-20Evolv-16725, title={Evolving thermostable reverse transcriptase activity in a DNA polymerase scaffold}, year={2006}, doi={10.1002/anie.200602772}, number={45}, volume={45}, issn={1433-7851}, journal={Angewandte Chemie International Edition}, pages={7633--7635}, author={Sauter, Katharina B. and Marx, Andreas} }
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| Sauter_167259.pdf | 138 |
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