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Reporter ribozymes for domain-specific-real-time analysis of biomolecular interactions : HIV-1-reverse transcriptase and the primer-template complex

Reporter ribozymes for domain-specific-real-time analysis of biomolecular interactions : HIV-1-reverse transcriptase and the primer-template complex

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HARTIG, Jörg, Michael FAMULOK, 2002. Reporter ribozymes for domain-specific-real-time analysis of biomolecular interactions : HIV-1-reverse transcriptase and the primer-template complex. In: Angewandte Chemie International Edition. 41(22), pp. 4263-4266. ISSN 1433-7851

@article{Hartig2002Repor-15660, title={Reporter ribozymes for domain-specific-real-time analysis of biomolecular interactions : HIV-1-reverse transcriptase and the primer-template complex}, year={2002}, doi={10.1002/1521-3773(20021115)41:22<4263::AID-ANIE4263>3.0.CO;2-7}, number={22}, volume={41}, issn={1433-7851}, journal={Angewandte Chemie International Edition}, pages={4263--4266}, author={Hartig, Jörg and Famulok, Michael} }

<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/15660"> <dc:creator>Famulok, Michael</dc:creator> <dc:language>eng</dc:language> <dcterms:abstract xml:lang="eng">By fusing an aptamer to a ribozyme, an aptazyme was constructed (see picture) which sensitively and specifically detects the presence of HIV-1 reverse transcriptase (RT). The fusion construct not only serves as a biosensor, but is also well suited for screening lead structures binding to the primer/template binding site of HIV-1 RT.</dcterms:abstract> <dcterms:bibliographicCitation>Ersch. in: Angewandte Chemie / International Edition ; 41 (2002), 22. - S. 4263-4266</dcterms:bibliographicCitation> <dc:contributor>Hartig, Jörg</dc:contributor> <dcterms:issued>2002</dcterms:issued> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-10-10T10:34:12Z</dc:date> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-10-10T10:34:12Z</dcterms:available> <dc:creator>Hartig, Jörg</dc:creator> <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/15660"/> <dc:contributor>Famulok, Michael</dc:contributor> <dcterms:rights rdf:resource="http://nbn-resolving.org/urn:nbn:de:bsz:352-20140905103605204-4002607-1"/> <dc:rights>deposit-license</dc:rights> <dcterms:title>Reporter ribozymes for domain-specific-real-time analysis of biomolecular interactions : HIV-1-reverse transcriptase and the primer-template complex</dcterms:title> </rdf:Description> </rdf:RDF>

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