Reporter ribozymes for domain-specific-real-time analysis of biomolecular interactions : HIV-1-reverse transcriptase and the primer-template complex

Lade...
Vorschaubild
Dateien
Zu diesem Dokument gibt es keine Dateien.
Datum
2002
Autor:innen
Famulok, Michael
Herausgeber:innen
Kontakt
ISSN der Zeitschrift
Electronic ISSN
ISBN
Bibliografische Daten
Verlag
Schriftenreihe
Auflagebezeichnung
ArXiv-ID
Internationale Patentnummer
Angaben zur Forschungsförderung
Projekt
Open Access-Veröffentlichung
Sammlungen
Core Facility der Universität Konstanz
Gesperrt bis
Titel in einer weiteren Sprache
Forschungsvorhaben
Organisationseinheiten
Zeitschriftenheft
Publikationstyp
Zeitschriftenartikel
Publikationsstatus
Published
Erschienen in
Angewandte Chemie International Edition. 2002, 41(22), pp. 4263-4266. ISSN 1433-7851. Available under: doi: 10.1002/1521-3773(20021115)41:22<4263::AID-ANIE4263>3.0.CO;2-7
Zusammenfassung

By fusing an aptamer to a ribozyme, an aptazyme was constructed (see picture) which sensitively and specifically detects the presence of HIV-1 reverse transcriptase (RT). The fusion construct not only serves as a biosensor, but is also well suited for screening lead structures binding to the primer/template binding site of HIV-1 RT.

Zusammenfassung in einer weiteren Sprache
Fachgebiet (DDC)
540 Chemie
Schlagwörter
hammerhead ribozyme, proteins, reverse transcriptase, ribozymes, RNA, RNA–protein interactions
Konferenz
Rezension
undefined / . - undefined, undefined
Zitieren
ISO 690HARTIG, Jörg S., Michael FAMULOK, 2002. Reporter ribozymes for domain-specific-real-time analysis of biomolecular interactions : HIV-1-reverse transcriptase and the primer-template complex. In: Angewandte Chemie International Edition. 2002, 41(22), pp. 4263-4266. ISSN 1433-7851. Available under: doi: 10.1002/1521-3773(20021115)41:22<4263::AID-ANIE4263>3.0.CO;2-7
BibTex
@article{Hartig2002Repor-15660,
  year={2002},
  doi={10.1002/1521-3773(20021115)41:22<4263::AID-ANIE4263>3.0.CO;2-7},
  title={Reporter ribozymes for domain-specific-real-time analysis of biomolecular interactions : HIV-1-reverse transcriptase and the primer-template complex},
  number={22},
  volume={41},
  issn={1433-7851},
  journal={Angewandte Chemie International Edition},
  pages={4263--4266},
  author={Hartig, Jörg S. and Famulok, Michael}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/15660">
    <dc:language>eng</dc:language>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-10-10T10:34:12Z</dcterms:available>
    <dcterms:bibliographicCitation>Ersch. in: Angewandte Chemie / International Edition ; 41 (2002), 22. - S. 4263-4266</dcterms:bibliographicCitation>
    <dc:creator>Famulok, Michael</dc:creator>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/29"/>
    <dc:contributor>Hartig, Jörg S.</dc:contributor>
    <dc:creator>Hartig, Jörg S.</dc:creator>
    <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/15660"/>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-10-10T10:34:12Z</dc:date>
    <dc:rights>terms-of-use</dc:rights>
    <dcterms:rights rdf:resource="https://rightsstatements.org/page/InC/1.0/"/>
    <dc:contributor>Famulok, Michael</dc:contributor>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <dcterms:abstract xml:lang="eng">By fusing an aptamer to a ribozyme, an aptazyme was constructed (see picture) which sensitively and specifically detects the presence of HIV-1 reverse transcriptase (RT). The fusion construct not only serves as a biosensor, but is also well suited for screening lead structures binding to the primer/template binding site of HIV-1 RT.</dcterms:abstract>
    <dcterms:issued>2002</dcterms:issued>
    <dcterms:title>Reporter ribozymes for domain-specific-real-time analysis of biomolecular interactions : HIV-1-reverse transcriptase and the primer-template complex</dcterms:title>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/29"/>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
  </rdf:Description>
</rdf:RDF>
Interner Vermerk
xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter
Kontakt
URL der Originalveröffentl.
Prüfdatum der URL
Prüfungsdatum der Dissertation
Finanzierungsart
Kommentar zur Publikation
Allianzlizenz
Corresponding Authors der Uni Konstanz vorhanden
Internationale Co-Autor:innen
Universitätsbibliographie
Nein
Begutachtet
Diese Publikation teilen