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Identification of toxic 2,4-decadienal in oxidized, low-density lipoprotein by solid-phase microextraction

Identification of toxic 2,4-decadienal in oxidized, low-density lipoprotein by solid-phase microextraction

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SPITELLER, Dieter, Gerhard SPITELLER, 2000. Identification of toxic 2,4-decadienal in oxidized, low-density lipoprotein by solid-phase microextraction. In: Angewandte Chemie International Edition. 39(3), pp. 583-585. ISSN 1433-7851

@article{Spiteller2000Ident-15586, title={Identification of toxic 2,4-decadienal in oxidized, low-density lipoprotein by solid-phase microextraction}, year={2000}, doi={10.1002/(SICI)1521-3773(20000204)39:3<583::AID-ANIE583>3.0.CO;2-O}, number={3}, volume={39}, issn={1433-7851}, journal={Angewandte Chemie International Edition}, pages={583--585}, author={Spiteller, Dieter and Spiteller, Gerhard} }

<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/15586"> <dc:contributor>Spiteller, Gerhard</dc:contributor> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-10-20T11:53:25Z</dc:date> <dc:rights>deposit-license</dc:rights> <dcterms:abstract xml:lang="eng">The oxidation of low-density lipoprotein (LDL) in vitro was studied by a combination of solid-phase microextraction and GC/MS. 2-trans,4-cis-2,4-Decadienal, which is strongly toxic in vitro, was detected as the early oxidation product. This compound is degraded further to hexanal and (by cyclization of 4-hydroxy-2-nonenal) to 2-pentylfuran.</dcterms:abstract> <dc:language>eng</dc:language> <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/15586"/> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-10-20T11:53:25Z</dcterms:available> <dc:creator>Spiteller, Dieter</dc:creator> <dc:creator>Spiteller, Gerhard</dc:creator> <dcterms:title>Identification of toxic 2,4-decadienal in oxidized, low-density lipoprotein by solid-phase microextraction</dcterms:title> <dcterms:bibliographicCitation>Publ. in: Angewandte Chemie / International edition : a journal of the Gesellschaft Deutscher Chemiker ; 39 (2000), 3. - S. 583-585</dcterms:bibliographicCitation> <dc:contributor>Spiteller, Dieter</dc:contributor> <dcterms:issued>2000</dcterms:issued> <dcterms:rights rdf:resource="http://nbn-resolving.org/urn:nbn:de:bsz:352-20140905103605204-4002607-1"/> </rdf:Description> </rdf:RDF>

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