KOPS - Das Institutionelle Repositorium der Universität Konstanz

Control of microtubule dynamics by the antagonistic activities of XMAP215 and XKCM1 in Xenopus egg extracts

Control of microtubule dynamics by the antagonistic activities of XMAP215 and XKCM1 in Xenopus egg extracts

Zitieren

Dateien zu dieser Ressource

Prüfsumme: MD5:dc212c49d787377573cccef11970bf8b

TOURNEBIZE, Régis, Andrei POPOV, Kazuhisa KINOSHITA, Anthony J. ASHFORD, Sonja RYBINA, Andrei POZNIAKOVSKY, Thomas U. MAYER, Claire E. WALCZAK, Eric KARSENTI, Anthony A. HYMAN, 2000. Control of microtubule dynamics by the antagonistic activities of XMAP215 and XKCM1 in Xenopus egg extracts. In: Nature Cell Biology. 2(1), pp. 13-19. ISSN 1465-7392

@article{Tournebize2000-01Contr-14055, title={Control of microtubule dynamics by the antagonistic activities of XMAP215 and XKCM1 in Xenopus egg extracts}, year={2000}, doi={10.1038/71330}, number={1}, volume={2}, issn={1465-7392}, journal={Nature Cell Biology}, pages={13--19}, author={Tournebize, Régis and Popov, Andrei and Kinoshita, Kazuhisa and Ashford, Anthony J. and Rybina, Sonja and Pozniakovsky, Andrei and Mayer, Thomas U. and Walczak, Claire E. and Karsenti, Eric and Hyman, Anthony A.} }

<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/14055"> <dc:contributor>Popov, Andrei</dc:contributor> <dc:language>eng</dc:language> <dcterms:issued>2000-01</dcterms:issued> <dcterms:title>Control of microtubule dynamics by the antagonistic activities of XMAP215 and XKCM1 in Xenopus egg extracts</dcterms:title> <dcterms:abstract xml:lang="eng">Microtubules are dynamic polymers that move stochastically between periods of growth and shrinkage, a property known as dynamic instability. Here, to investigate the mechanisms regulating microtubule dynamics in Xenopus egg extracts, we have cloned the complementary DNA encoding the microtubule-associated protein XMAP215 and investigated the function of the XMAP215 protein. Immunodepletion of XMAP215 indicated that it is a major microtubule-stabilizing factor in Xenopus egg extracts. During interphase, XMAP215 stabilizes microtubules primarily by opposing the activity of the destabilizing factor XKCM1, a member of the kinesin superfamily. These results indicate that microtubule dynamics in Xenopus egg extracts are regulated by a balance between a stabilizing factor, XMAP215, and a destabilizing factor, XKCM1.</dcterms:abstract> <dcterms:bibliographicCitation>Nature Cell Biology ; 2 (2000), 1. - S. 13-19</dcterms:bibliographicCitation> <dc:contributor>Pozniakovsky, Andrei</dc:contributor> <dc:creator>Walczak, Claire E.</dc:creator> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2012-01-11T11:04:31Z</dc:date> <dc:contributor>Hyman, Anthony A.</dc:contributor> <dc:creator>Ashford, Anthony J.</dc:creator> <dc:contributor>Ashford, Anthony J.</dc:contributor> <dc:contributor>Walczak, Claire E.</dc:contributor> <dc:creator>Tournebize, Régis</dc:creator> <dc:contributor>Karsenti, Eric</dc:contributor> <dc:contributor>Rybina, Sonja</dc:contributor> <dc:creator>Popov, Andrei</dc:creator> <dc:creator>Karsenti, Eric</dc:creator> <dc:creator>Kinoshita, Kazuhisa</dc:creator> <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/14055"/> <dc:contributor>Tournebize, Régis</dc:contributor> <dc:creator>Pozniakovsky, Andrei</dc:creator> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2012-01-11T11:04:31Z</dcterms:available> <dc:creator>Mayer, Thomas U.</dc:creator> <dc:rights>deposit-license</dc:rights> <dcterms:rights rdf:resource="http://nbn-resolving.org/urn:nbn:de:bsz:352-20140905103605204-4002607-1"/> <dc:contributor>Mayer, Thomas U.</dc:contributor> <dc:contributor>Kinoshita, Kazuhisa</dc:contributor> <dc:creator>Rybina, Sonja</dc:creator> <dc:creator>Hyman, Anthony A.</dc:creator> </rdf:Description> </rdf:RDF>

Dateiabrufe seit 01.10.2014 (Informationen über die Zugriffsstatistik)

Tournebize_140552.pdf 78

Das Dokument erscheint in:

KOPS Suche


Stöbern

Mein Benutzerkonto