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Electrophysiological Evidence for a Syntactic but Not a Semantic Deficit in Patients with Major Depression

Electrophysiological Evidence for a Syntactic but Not a Semantic Deficit in Patients with Major Depression

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RUCHSOW, Martin, Georg GROEN, Manfred SPITZER, Leopold HERMLE, Anna BUCHHEIM, Markus KIEFER, 2008. Electrophysiological Evidence for a Syntactic but Not a Semantic Deficit in Patients with Major Depression. In: Journal of Psychophysiology. 22(3), pp. 121-129

@article{Ruchsow2008Elect-1355, title={Electrophysiological Evidence for a Syntactic but Not a Semantic Deficit in Patients with Major Depression}, year={2008}, doi={10.1027/0269-8803.22.3.121}, number={3}, volume={22}, journal={Journal of Psychophysiology}, pages={121--129}, author={Ruchsow, Martin and Groen, Georg and Spitzer, Manfred and Hermle, Leopold and Buchheim, Anna and Kiefer, Markus} }

<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/1355"> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-23T09:24:55Z</dc:date> <dc:contributor>Buchheim, Anna</dc:contributor> <dc:creator>Ruchsow, Martin</dc:creator> <dc:contributor>Ruchsow, Martin</dc:contributor> <dc:creator>Spitzer, Manfred</dc:creator> <dc:language>eng</dc:language> <dc:creator>Buchheim, Anna</dc:creator> <dcterms:issued>2008</dcterms:issued> <dc:contributor>Hermle, Leopold</dc:contributor> <dcterms:title>Electrophysiological Evidence for a Syntactic but Not a Semantic Deficit in Patients with Major Depression</dcterms:title> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-23T09:24:55Z</dcterms:available> <dc:contributor>Kiefer, Markus</dc:contributor> <dc:creator>Hermle, Leopold</dc:creator> <dcterms:bibliographicCitation>Publ. in: Journal of Psychophysiology, 22 (2008), 3, pp. 121-129</dcterms:bibliographicCitation> <dc:contributor>Spitzer, Manfred</dc:contributor> <dc:creator>Groen, Georg</dc:creator> <dcterms:abstract xml:lang="eng">Cognitive deficits are common in patients with major depression. The present study investigated whether these impairments also comprise language processes such as sentence comprehension. We studied four language-related evoked potentials (early left anterior negativity [ELAN], N400, left anterior negativity [LAN], and P600) in 14 patients with major depressive disorder (MDD) in partial remission and 14 matched healthy controls using a sentence paradigm with correct, semantic mismatching, and syntactic mismatching sentences. In contrast to controls, patients showed no significant P600 effect when comparing syntactic mismatching and correct sentences. No group differences could be observed for the ELAN, N400, and LAN components. The missing P600 effect may indicate deficits in the cognitive domain of language processing in depressive patients or impairment of a more general process to detect deviances from regularities. How this result integrates into the concept of a general cognitive deficit in major depression remains a goal for future studies.</dcterms:abstract> <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/1355"/> <dc:creator>Kiefer, Markus</dc:creator> <dc:contributor>Groen, Georg</dc:contributor> <dcterms:rights rdf:resource="http://nbn-resolving.org/urn:nbn:de:bsz:352-20140905103416863-3868037-7"/> <dc:rights>deposit-license</dc:rights> </rdf:Description> </rdf:RDF>

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