Synthesis of Water-Soluble Phosphinophenol for Traceless Staudinger Ligation
| Type of Publication: | Journal article |
| URI (citable link): | http://nbn-resolving.de/urn:nbn:de:bsz:352-126020 |
| Author: | Weisbrod, Samuel H.; Marx, Andreas |
| Year of publication: | 2010 |
| Published in: | Synlett ; 2010 (2010), 05. - pp. 787-789. - ISSN 0936-5214 |
| DOI (citable link): | https://dx.doi.org/10.1055/s-0029-1219353 |
| Summary: |
The traceless Staudinger ligation can be mediated in water without organic co-solvents if charged groups render the phenylphosphine reagent water soluble. Here the synthesis of a new water-soluble phosphine is presented based on a diphenylphosphinophenol reagent. Staudinger ligation with this reagent and azido glycine amide showed conversion of 77%.
|
| Subject (DDC): | 540 Chemistry |
| Keywords: | amide, phenol, Staudinger ligation, conjugation, phosphine |
| Link to License: | In Copyright |
| Bibliography of Konstanz: | Yes |
Cite This
Files in this item
![[PDF]](/themes/Kops/images/mimes/pdf.png "PDF file"){kind=small}
WEISBROD, Samuel H., Andreas MARX, 2010. Synthesis of Water-Soluble Phosphinophenol for Traceless Staudinger Ligation. In: Synlett. 2010(05), pp. 787-789. ISSN 0936-5214. Available under: doi: 10.1055/s-0029-1219353
@article{Weisbrod2010Synth-12602, title={Synthesis of Water-Soluble Phosphinophenol for Traceless Staudinger Ligation}, year={2010}, doi={10.1055/s-0029-1219353}, number={05}, volume={2010}, issn={0936-5214}, journal={Synlett}, pages={787--789}, author={Weisbrod, Samuel H. and Marx, Andreas} }
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#" xmlns:foaf="http://xmlns.com/foaf/0.1/" xmlns:void="http://rdfs.org/ns/void#" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/12602"> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-06-16T08:53:55Z</dcterms:available> <foaf:homepage rdf:resource="http://localhost:8080/jspui"/> <dc:creator>Marx, Andreas</dc:creator> <dcterms:abstract xml:lang="eng">The traceless Staudinger ligation can be mediated in water without organic co-solvents if charged groups render the phenylphosphine reagent water soluble. Here the synthesis of a new water-soluble phosphine is presented based on a diphenylphosphinophenol reagent. Staudinger ligation with this reagent and azido glycine amide showed conversion of 77%.</dcterms:abstract> <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/12602"/> <dc:rights>terms-of-use</dc:rights> <dc:contributor>Weisbrod, Samuel H.</dc:contributor> <dcterms:issued>2010</dcterms:issued> <dc:language>eng</dc:language> <dcterms:rights rdf:resource="https://rightsstatements.org/page/InC/1.0/"/> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-06-16T08:53:55Z</dc:date> <dcterms:bibliographicCitation>First publ. in: Synlett 5 (2010), pp.787-789</dcterms:bibliographicCitation> <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/12602/2/Weisbrod_126020.pdf"/> <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/29"/> <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/29"/> <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/> <dc:contributor>Marx, Andreas</dc:contributor> <dc:creator>Weisbrod, Samuel H.</dc:creator> <dcterms:title>Synthesis of Water-Soluble Phosphinophenol for Traceless Staudinger Ligation</dcterms:title> <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/12602/2/Weisbrod_126020.pdf"/> </rdf:Description> </rdf:RDF>
Downloads since Oct 1, 2014 (Information about access statistics)
| Weisbrod_126020.pdf | 297 |
This item appears in the following Collection(s)
Search KOPS
Browse
My Account
