KOPS - Das Institutionelle Repositorium der Universität Konstanz

Methohexital-Induced Changes in Spectral Power of Neuromagnetic Signals : Beta Augmentation is Smaller Over the Hemisphere Containing the Epileptogenic Focus

Methohexital-Induced Changes in Spectral Power of Neuromagnetic Signals : Beta Augmentation is Smaller Over the Hemisphere Containing the Epileptogenic Focus

Zitieren

Dateien zu dieser Ressource

Prüfsumme: MD5:197adcf9ce34329dc930979aef52a6ee

WIENBRUCH, Christian, Carsten EULITZ, Klaus LEHNERTZ, Anke BROCKHAUS, Christian E. ELGER, Thomas ELBERT, Manfried HOKE, 1997. Methohexital-Induced Changes in Spectral Power of Neuromagnetic Signals : Beta Augmentation is Smaller Over the Hemisphere Containing the Epileptogenic Focus. In: Brain Topography. 10(1), pp. 41-47. ISSN 0896-0267. eISSN 1573-6792

@article{Wienbruch1997Metho-11256, title={Methohexital-Induced Changes in Spectral Power of Neuromagnetic Signals : Beta Augmentation is Smaller Over the Hemisphere Containing the Epileptogenic Focus}, year={1997}, number={1}, volume={10}, issn={0896-0267}, journal={Brain Topography}, pages={41--47}, author={Wienbruch, Christian and Eulitz, Carsten and Lehnertz, Klaus and Brockhaus, Anke and Elger, Christian E. and Elbert, Thomas and Hoke, Manfried} }

<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#" xmlns:foaf="http://xmlns.com/foaf/0.1/" xmlns:void="http://rdfs.org/ns/void#" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/11256"> <dc:creator>Elger, Christian E.</dc:creator> <dc:format>application/pdf</dc:format> <dc:creator>Wienbruch, Christian</dc:creator> <dc:contributor>Brockhaus, Anke</dc:contributor> <dcterms:title>Methohexital-Induced Changes in Spectral Power of Neuromagnetic Signals : Beta Augmentation is Smaller Over the Hemisphere Containing the Epileptogenic Focus</dcterms:title> <dc:contributor>Elger, Christian E.</dc:contributor> <dc:rights>deposit-license</dc:rights> <dc:contributor>Hoke, Manfried</dc:contributor> <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/43"/> <foaf:homepage rdf:resource="http://localhost:8080/jspui"/> <dcterms:issued>1997</dcterms:issued> <dc:contributor>Eulitz, Carsten</dc:contributor> <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/11256/1/Wienbruch_et_al_Epil_1997.pdf"/> <dc:creator>Hoke, Manfried</dc:creator> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-25T09:26:44Z</dc:date> <dc:creator>Brockhaus, Anke</dc:creator> <dc:creator>Elbert, Thomas</dc:creator> <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/11256/1/Wienbruch_et_al_Epil_1997.pdf"/> <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-25T09:26:44Z</dcterms:available> <dc:creator>Eulitz, Carsten</dc:creator> <dc:contributor>Lehnertz, Klaus</dc:contributor> <dc:creator>Lehnertz, Klaus</dc:creator> <dc:contributor>Elbert, Thomas</dc:contributor> <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/11256"/> <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/43"/> <dcterms:abstract xml:lang="eng">Previous research has suggested that methohexital, a short-term barbiturate, alters activity in the primary epileptogenic area. It can be assumed that drug-induced activation of the epileptogenic focus provides a rapid and safe method to obtain a sufficient amount of information relevant for the lateralization and localisation of the primary epileptogenic area. This study shows that methohexital changes spectral power in the beta band derived from magnetoencephalographic (MEG) signals over the hemisphere ipsilateral to the primary epileptogenic area. This effect was demonstrated for 10/13 of the investigated patients suffering from unilateral temporal lobe epilepsy (TLE). The side and location of the primary epileptogenic area of these patients (5 left TLE, 8 right TLE) was determined invasively during presurgical evaluation. During a 1-2 minute interval after intravenous bolus injection of 100 mg methohexital a clear lateralization effect in the beta band was observed, which differed maginally between fronto-central, fronto-temporal and temporo-parietal brain regions. Analyses of simultaneously recorded scalp electroencephalographic (EEG) data revealed effects consistent with those of the MEG anasysis. The reduced enhancement of beta band spectral power of MEG recordings provides a potential application for the non-invasive lateralization of the primary epileptogenic area.</dcterms:abstract> <dcterms:bibliographicCitation>Brain Topography ; 10 (1997), 1. - S. 41-47</dcterms:bibliographicCitation> <dc:language>eng</dc:language> <dc:contributor>Wienbruch, Christian</dc:contributor> <dcterms:rights rdf:resource="http://nbn-resolving.org/urn:nbn:de:bsz:352-20140905103416863-3868037-7"/> </rdf:Description> </rdf:RDF>

Dateiabrufe seit 01.10.2014 (Informationen über die Zugriffsstatistik)

Wienbruch_et_al_Epil_1997.pdf 103

Das Dokument erscheint in:

KOPS Suche


Stöbern

Mein Benutzerkonto