Type of Publication: | Journal article |
URI (citable link): | http://nbn-resolving.de/urn:nbn:de:bsz:352-opus-64547 |
Author: | Rockstroh, Brigitte; Kissler, Johanna; Mohr, Bettina; Eulitz, Carsten; Lommen, Ursula; Wienbruch, Christian; Cohen, Rudolf; Elbert, Thomas |
Year of publication: | 2001 |
Published in: | Biological Psychiatry ; 49 (2001), 8. - pp. 694-703 |
DOI (citable link): | https://dx.doi.org/10.1016/S0006-3223(00)01023-4 |
Summary: |
Background: A growing body of literature suggests that schizophrenic patients often do not show the normal brain hemispheric asymmetry. We have found this for simple tones presented to the right ear in a previous study. In this study we extended this investigation to left ear stimulation and verbal stimuli. Methods: With a whole-head neuromagnetometer, contra- and ipsilateral auditory-evoked magnetic fields in response to tones (1000 Hz) and to the syllables (ba) delivered to the left and right ears in separate runs were compared between schizophrenic patients (n = 17) and healthy control subjects (n = 15). Results: In response to tones, all control subjects showed the expected asymmetry (contralateral predominance) of the auditory-evoked magnetic N100m (dipole moment). In the patient sample asymmetry was reversed following tones presented to the left ear in 47% and following tones to the right ear in 24%. In response to syllables, the asymmetry was similar between groups. In patients compared with control subjects the N100m was located more anterior without asymmetry between hemispheres. Conclusions: Results suggest that deviation from the normal functional lateralization in schizophrenia appears in a proportion of patients at a basic stage of auditory processing, but may be compensated for at higher levels such as the processing of syllables.
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Subject (DDC): | 150 Psychology |
Keywords: | Schizophrenia, magnetoencephalography, hemispheric asymmetry, N100m, syllables, auditory, verbal processing, tone perception |
Link to License: | Attribution-NonCommercial-NoDerivs 2.0 Generic |
Bibliography of Konstanz: | Yes |
ROCKSTROH, Brigitte, Johanna KISSLER, Bettina MOHR, Carsten EULITZ, Ursula LOMMEN, Christian WIENBRUCH, Rudolf COHEN, Thomas ELBERT, 2001. Altered Hemispheric Asymmetry of Auditory Magnetic Fields to Tones and Syllables in Schizophrenia. In: Biological Psychiatry. 49(8), pp. 694-703. Available under: doi: 10.1016/S0006-3223(00)01023-4
@article{Rockstroh2001Alter-10941, title={Altered Hemispheric Asymmetry of Auditory Magnetic Fields to Tones and Syllables in Schizophrenia}, year={2001}, doi={10.1016/S0006-3223(00)01023-4}, number={8}, volume={49}, journal={Biological Psychiatry}, pages={694--703}, author={Rockstroh, Brigitte and Kissler, Johanna and Mohr, Bettina and Eulitz, Carsten and Lommen, Ursula and Wienbruch, Christian and Cohen, Rudolf and Elbert, Thomas} }
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Elbert_2001_Altered_Hemispheric.pdf | 413 |