Molecular Visualization in the Rational Drug Design Process

Keil, Matthias; Marhofer, Richard J.; Rohwer, Andreas; Selzer, Paul M.; Brickmann, Jürgen; Korb, Oliver; Exner, Thomas E.

Molecular Visualization in the Rational Drug Design Process

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Date

2009

Authors

Keil, Matthias

Marhofer, Richard J.

Rohwer, Andreas

Selzer, Paul M.

Brickmann, Jürgen

Korb, Oliver

Exner, Thomas E.

Project

Plants-Software

Collections

Chemie
Zukunftskolleg

Publication type

Journal article

Published in

Frontiers in Bioscience ; 14 (2009), 14. - pp. 2559-2583. - ISSN 1093-9946. - eISSN 1093-4715

Abstract

The visualization of molecular scenarios on an atomic level can help to interpret experimental and theoretical findings. This is demonstrated in this review article with the specific field of drug design. State-of-the-art visualization techniques are described and applied to the different stages of the rational design process. Numerous examples from the literature, in which visualization was used as a major tool in the data analysis and interpretation, are provided to show that images are not only useful for

Subject (DDC)

540 Chemistry

Cite This

ISO 690

KEIL, Matthias, Richard J. MARHOFER, Andreas ROHWER, Paul M. SELZER, Jürgen BRICKMANN, Oliver KORB, Thomas E. EXNER, 2009. Molecular Visualization in the Rational Drug Design Process. In: Frontiers in Bioscience. 14(14), pp. 2559-2583. ISSN 1093-9946. eISSN 1093-4715. Available under: doi: 10.2741/3398

BibTex

@article{Keil2009Molec-1090,
  year={2009},
  doi={10.2741/3398},
  title={Molecular Visualization in the Rational Drug Design Process},
  number={14},
  volume={14},
  issn={1093-9946},
  journal={Frontiers in Bioscience},
  pages={2559--2583},
  author={Keil, Matthias and Marhofer, Richard J. and Rohwer, Andreas and Selzer, Paul M. and Brickmann, Jürgen and Korb, Oliver and Exner, Thomas E.}
}

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Bibliography of Konstanz

Yes