Affective blindsight : intact fear conditioning to a visual cue in a cortically blind patient

Hamm, Alfons; Weike, Almut I.; Schupp, Harald T.; Treig, Thomas; Dressel, Alexander; Kessler, Christof

Affective blindsight : intact fear conditioning to a visual cue in a cortically blind patient

Dateien

Hamm_et_al2003.pdfGröße: 288.5 KBDownloads: 939

Datum

2003

Autor:innen

Hamm, Alfons

Weike, Almut I.

Schupp, Harald T.

Treig, Thomas

Dressel, Alexander

Kessler, Christof

Publikationstyp

Zeitschriftenartikel

unikn.publication.listelement.citation.prefix.version.undefined

Brain. 2003, 126, pp. 267-275

Zusammenfassung

Blindsight refers to remarkable residual visual abilities of patients with damage to the primary visual cortex (V1). Recent studies revealed that such residual abilities do not apply only to relatively simple object discriminations, but that these patients can also differentially categorize and respond to emotionally salient stimuli. The current study reports on a case of intact fear conditioning to a visual cue in a male patient with complete bilateral cortical blindness. The patient was admitted to the stroke unit of the neurological department because of complete loss of vision. Both CT and structural MRI scans confirmed lesions in both territories of the posterior cerebral artery. No visual evoked potentials could be detected confirming complete cortical blindness. During fear conditioning, a visual cue predicted the occurrence of an aversive electric shock. Acoustic startle probes were presented during and between the conditioned stimuli. Relative to the control condition, startle reflexes were substantially potentiated when elicited in the presence of the conditioned stimuli. No such potentiation was observed prior to conditioning. These data suggest that fear learning to visual cues does not require a cortical representation of the conditioned stimulus in the primary sensory cortex and that subcortical pathways are sufficient to activate the fear module in humans.

Fachgebiet (DDC)

150 Psychologie

Schlagwörter

X-Ray Computed, Conditioning, Classical, Evoked Potentials, Visual, Tomography, X-Ray Computed, Blindness, Cortical/physiopathology/

Zitieren

ISO 690

HAMM, Alfons, Almut I. WEIKE, Harald T. SCHUPP, Thomas TREIG, Alexander DRESSEL, Christof KESSLER, 2003. Affective blindsight : intact fear conditioning to a visual cue in a cortically blind patient. In: Brain. 2003, 126, pp. 267-275

BibTex

@article{Hamm2003Affec-10691,
  year={2003},
  title={Affective blindsight : intact fear conditioning to a visual cue in a cortically blind patient},
  volume={126},
  journal={Brain},
  pages={267--275},
  author={Hamm, Alfons and Weike, Almut I. and Schupp, Harald T. and Treig, Thomas and Dressel, Alexander and Kessler, Christof}
}

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