KOPS - The Institutional Repository of the University of Konstanz

Possibilities and limitations of magnetic source imaging of methohexital-induced epileptiform patterns in temporal lobe epilepsy patients

Aufgrund von Vorbereitungen auf eine neue Version von KOPS, können kommenden Montag und Dienstag keine Publikationen eingereicht werden. (Due to preparations for a new version of KOPS, no publications can be submitted next Monday and Tuesday.)

Possibilities and limitations of magnetic source imaging of methohexital-induced epileptiform patterns in temporal lobe epilepsy patients

Cite This

Files in this item

Checksum: MD5:c2b208280ef2adbc036d18cce6187c86

BROCKHAUS, Anke, Klaus LEHNERTZ, Christian WIENBRUCH, Zbigniew J. KOWALIK, Wieland BURR, Thomas ELBERT, M. HOKE, Christian E. ELGER, 1997. Possibilities and limitations of magnetic source imaging of methohexital-induced epileptiform patterns in temporal lobe epilepsy patients. In: Electroencephalography and clinical Neuropsychology. 102, pp. 423-436. Available under: doi: 10.1016/S0921-884X(97)96625-X

@article{Brockhaus1997Possi-10614, title={Possibilities and limitations of magnetic source imaging of methohexital-induced epileptiform patterns in temporal lobe epilepsy patients}, year={1997}, doi={10.1016/S0921-884X(97)96625-X}, volume={102}, journal={Electroencephalography and clinical Neuropsychology}, pages={423--436}, author={Brockhaus, Anke and Lehnertz, Klaus and Wienbruch, Christian and Kowalik, Zbigniew J. and Burr, Wieland and Elbert, Thomas and Hoke, M. and Elger, Christian E.} }

<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#" xmlns:foaf="http://xmlns.com/foaf/0.1/" xmlns:void="http://rdfs.org/ns/void#" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/10614"> <dc:contributor>Wienbruch, Christian</dc:contributor> <dc:contributor>Elger, Christian E.</dc:contributor> <dcterms:bibliographicCitation>First publ. in: Electroencephalography and clinical Neuropsychology 102 (1997) 423-436</dcterms:bibliographicCitation> <dc:creator>Hoke, M.</dc:creator> <dcterms:abstract xml:lang="eng">The usefulness of MEG-based techniques in lateralizing and localizing the epileptogenic area was investigated in the present study. Spontaneous and methohexital-induced spikes were studied in a group of 15 patients with temporomesial epilepsy using a 37-channel neuromagnetometer. The accuracy of the magnetic source imaging was compared to the results of electrocorticographic (ECoG) recordings. Differences of drug-induced spike densities in the MEG recordings between both sides confirmed a similar lateralizing power of the MEG and ECoG recordings. Source location analyses based on a moving dipole model resp. a rotating dipole model were performed using a spherical head model. After subdivision of the volume of each patient's head, 8 qcm cubicles containing at least 3 source locations were projected onto the individual MRI scan and resulted in source locations within or close to the presurgically defined primary epileptogenic area only in 3 of the 15 patients. Spike induction by methohexital has the advantage of shortening the recording period as compared to recordings of interictal epileptiform discharges. However, the correlation analyses of spike densities from MEG and ECoG recordings and the source location analyses from MEG recordings indicate that spikes generated in deep temporomesial structures may escape the MEG registration.</dcterms:abstract> <dcterms:title>Possibilities and limitations of magnetic source imaging of methohexital-induced epileptiform patterns in temporal lobe epilepsy patients</dcterms:title> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-25T09:20:04Z</dcterms:available> <dc:contributor>Burr, Wieland</dc:contributor> <dc:creator>Wienbruch, Christian</dc:creator> <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/10614"/> <dcterms:rights rdf:resource="https://rightsstatements.org/page/InC/1.0/"/> <dc:creator>Kowalik, Zbigniew J.</dc:creator> <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/> <dc:contributor>Brockhaus, Anke</dc:contributor> <dc:creator>Elger, Christian E.</dc:creator> <dc:rights>terms-of-use</dc:rights> <foaf:homepage rdf:resource="http://localhost:8080/jspui"/> <dc:contributor>Lehnertz, Klaus</dc:contributor> <dc:contributor>Kowalik, Zbigniew J.</dc:contributor> <dc:format>application/pdf</dc:format> <dc:creator>Elbert, Thomas</dc:creator> <dcterms:issued>1997</dcterms:issued> <dc:creator>Burr, Wieland</dc:creator> <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/10614/1/Brockhaus_et_al_97.pdf"/> <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/10614/1/Brockhaus_et_al_97.pdf"/> <dc:contributor>Elbert, Thomas</dc:contributor> <dc:contributor>Hoke, M.</dc:contributor> <dc:creator>Lehnertz, Klaus</dc:creator> <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/43"/> <dc:language>eng</dc:language> <dc:creator>Brockhaus, Anke</dc:creator> <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/43"/> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-25T09:20:04Z</dc:date> </rdf:Description> </rdf:RDF>

Downloads since Oct 1, 2014 (Information about access statistics)

Brockhaus_et_al_97.pdf 575

This item appears in the following Collection(s)

Search KOPS


Browse

My Account