Steric Constraints Dependent on Nucleobase Pair Orientation Vary in Different DNA Polymerase Active Sites
| Type of Publication: | Journal article |
| URI (citable link): | http://nbn-resolving.de/urn:nbn:de:bsz:352-opus-86768 |
| Author: | Streckenbach, Frank; Rangam, Gopinath; Möller, Heiko M.; Marx, Andreas |
| Year of publication: | 2009 |
| Published in: | ChemBioChem ; 10 (2009), 10. - pp. 1630-1633. - ISSN 1439-4227. - eISSN 1439-7633 |
| Pubmed ID: | 19544344 |
| DOI (citable link): | https://dx.doi.org/10.1002/cbic.200900123 |
| Summary: |
Finding the right fit: Herein, we report on the development of novel steric probes and present initial insights into their interplay with DNA polymerases. Our findings provide experimental evidence for varied enzyme-substrate interactions that might account for the varied selectivity previously observed.
|
| Subject (DDC): | 540 Chemistry |
| Keywords: | base pairing, DNA polymerase, DNA replication, steric effects, steric hindranc |
| Link to License: | In Copyright |
| Bibliography of Konstanz: | Yes |
Cite This
Files in this item
![[PDF]](/themes/Kops/images/mimes/pdf.png "PDF file"){kind=small}
STRECKENBACH, Frank, Gopinath RANGAM, Heiko M. MÖLLER, Andreas MARX, 2009. Steric Constraints Dependent on Nucleobase Pair Orientation Vary in Different DNA Polymerase Active Sites. In: ChemBioChem. 10(10), pp. 1630-1633. ISSN 1439-4227. eISSN 1439-7633. Available under: doi: 10.1002/cbic.200900123
@article{Streckenbach2009Steri-1020, title={Steric Constraints Dependent on Nucleobase Pair Orientation Vary in Different DNA Polymerase Active Sites}, year={2009}, doi={10.1002/cbic.200900123}, number={10}, volume={10}, issn={1439-4227}, journal={ChemBioChem}, pages={1630--1633}, author={Streckenbach, Frank and Rangam, Gopinath and Möller, Heiko M. and Marx, Andreas} }
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#" xmlns:foaf="http://xmlns.com/foaf/0.1/" xmlns:void="http://rdfs.org/ns/void#" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/1020"> <dc:rights>terms-of-use</dc:rights> <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/1020/1/Streckenbach_86768.pdf"/> <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/29"/> <dc:creator>Rangam, Gopinath</dc:creator> <dcterms:bibliographicCitation>ChemBioChem ; 10 (2009), 10. - pp. 1630-1633</dcterms:bibliographicCitation> <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/29"/> <dc:contributor>Streckenbach, Frank</dc:contributor> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-22T17:54:47Z</dcterms:available> <dc:contributor>Rangam, Gopinath</dc:contributor> <dc:creator>Streckenbach, Frank</dc:creator> <dcterms:issued>2009</dcterms:issued> <dc:contributor>Marx, Andreas</dc:contributor> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-22T17:54:47Z</dc:date> <dc:language>eng</dc:language> <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/> <dc:creator>Marx, Andreas</dc:creator> <dcterms:abstract xml:lang="eng">Finding the right fit: Herein, we report on the development of novel steric probes and present initial insights into their interplay with DNA polymerases. Our findings provide experimental evidence for varied enzyme-substrate interactions that might account for the varied selectivity previously observed.</dcterms:abstract> <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/1020"/> <dcterms:title>Steric Constraints Dependent on Nucleobase Pair Orientation Vary in Different DNA Polymerase Active Sites</dcterms:title> <dcterms:rights rdf:resource="https://rightsstatements.org/page/InC/1.0/"/> <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/1020/1/Streckenbach_86768.pdf"/> <dc:creator>Möller, Heiko M.</dc:creator> <foaf:homepage rdf:resource="http://localhost:8080/jspui"/> <dc:contributor>Möller, Heiko M.</dc:contributor> </rdf:Description> </rdf:RDF>
Downloads since Oct 1, 2014 (Information about access statistics)
| Streckenbach_86768.pdf | 710 |
This item appears in the following Collection(s)
Search KOPS
Browse
My Account
