Steric Constraints Dependent on Nucleobase Pair Orientation Vary in Different DNA Polymerase Active Sites
| Type of Publication: | Journal article |
| URI (citable link): | http://nbn-resolving.de/urn:nbn:de:bsz:352-opus-86768 |
| Author: | Streckenbach, Frank; Rangam, Gopinath; Möller, Heiko M.; Marx, Andreas |
| Year of publication: | 2009 |
| Published in: | ChemBioChem ; 10 (2009), 10. - pp. 1630-1633. - ISSN 1439-4227. - eISSN 1439-7633 |
| Pubmed ID: | 19544344 |
| DOI (citable link): | https://dx.doi.org/10.1002/cbic.200900123 |
| Summary: |
Finding the right fit: Herein, we report on the development of novel steric probes and present initial insights into their interplay with DNA polymerases. Our findings provide experimental evidence for varied enzyme-substrate interactions that might account for the varied selectivity previously observed.
|
| Subject (DDC): | 540 Chemistry |
| Keywords: | base pairing, DNA polymerase, DNA replication, steric effects, steric hindranc |
| Link to License: | Terms of use |
| Bibliography of Konstanz: | Yes |
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STRECKENBACH, Frank, Gopinath RANGAM, Heiko M. MÖLLER, Andreas MARX, 2009. Steric Constraints Dependent on Nucleobase Pair Orientation Vary in Different DNA Polymerase Active Sites. In: ChemBioChem. 10(10), pp. 1630-1633. ISSN 1439-4227. eISSN 1439-7633. Available under: doi: 10.1002/cbic.200900123
@article{Streckenbach2009Steri-1020, title={Steric Constraints Dependent on Nucleobase Pair Orientation Vary in Different DNA Polymerase Active Sites}, year={2009}, doi={10.1002/cbic.200900123}, number={10}, volume={10}, issn={1439-4227}, journal={ChemBioChem}, pages={1630--1633}, author={Streckenbach, Frank and Rangam, Gopinath and Möller, Heiko M. and Marx, Andreas} }
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