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Synthesis of DNA Strands Site-Specifically Damaged by C8-Arylamine Purine Adducts and Effects on Various DNA Polymerases

Synthesis of DNA Strands Site-Specifically Damaged by C8-Arylamine Purine Adducts and Effects on Various DNA Polymerases

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BÖGE, Nicolas, Maike I. JACOBSEN, Zita SZOMBATI, Sabrina BAERNS, Francesca DI PASQUALE, Andreas MARX, Chris MEIER, 2008. Synthesis of DNA Strands Site-Specifically Damaged by C8-Arylamine Purine Adducts and Effects on Various DNA Polymerases. In: Chemistry : a European Journal. 14(35), pp. 11194-11208. ISSN 0947-6539. eISSN 1521-3765

@article{Boge2008Synth-1019, title={Synthesis of DNA Strands Site-Specifically Damaged by C8-Arylamine Purine Adducts and Effects on Various DNA Polymerases}, year={2008}, doi={10.1002/chem.200800979}, number={35}, volume={14}, issn={0947-6539}, journal={Chemistry : a European Journal}, pages={11194--11208}, author={Böge, Nicolas and Jacobsen, Maike I. and Szombati, Zita and Baerns, Sabrina and Di Pasquale, Francesca and Marx, Andreas and Meier, Chris} }

<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/1019"> <dc:contributor>Böge, Nicolas</dc:contributor> <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/1019"/> <dc:language>eng</dc:language> <dcterms:bibliographicCitation>First publ. in: Chemistry 14 (2008), 35, pp. 11194-11208</dcterms:bibliographicCitation> <dc:creator>Meier, Chris</dc:creator> <dcterms:issued>2008</dcterms:issued> <dcterms:abstract xml:lang="eng">C8-Arylamine-dG and C8-arylamine-dA adducts have been prepared using palladium cross-coupling chemistry. These adducts were subsequently converted into the corresponding 5'-O-DMTr-C8-arylamine-3'-O-phosphoramidites and then used for the automated synthesis of different site-specifically modified oligonucleotides. These "damaged" oligonucleotides have been characterized by ESI-MS, UV thermal stability assays, and circular dichroism, and they have been used in EcoRI assays as well as in primer extension studies using various DNA polymerases.</dcterms:abstract> <dc:creator>Jacobsen, Maike I.</dc:creator> <dcterms:rights rdf:resource="http://nbn-resolving.org/urn:nbn:de:bsz:352-20140905103416863-3868037-7"/> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-22T17:54:47Z</dcterms:available> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-22T17:54:47Z</dc:date> <dc:creator>Böge, Nicolas</dc:creator> <dc:contributor>Di Pasquale, Francesca</dc:contributor> <dcterms:title>Synthesis of DNA Strands Site-Specifically Damaged by C8-Arylamine Purine Adducts and Effects on Various DNA Polymerases</dcterms:title> <dc:contributor>Marx, Andreas</dc:contributor> <dc:creator>Di Pasquale, Francesca</dc:creator> <dc:rights>deposit-license</dc:rights> <dc:contributor>Meier, Chris</dc:contributor> <dc:contributor>Jacobsen, Maike I.</dc:contributor> <dc:contributor>Szombati, Zita</dc:contributor> <dc:creator>Szombati, Zita</dc:creator> <dc:contributor>Baerns, Sabrina</dc:contributor> <dc:creator>Marx, Andreas</dc:creator> <dc:creator>Baerns, Sabrina</dc:creator> </rdf:Description> </rdf:RDF>

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