KOPS - Das Institutionelle Repositorium der Universität Konstanz

Spatial Screening of Lectin Ligands : Cyclic Peptides as Scaffolds for Multivalent Presentation of Carbohydrates

Spatial Screening of Lectin Ligands : Cyclic Peptides as Scaffolds for Multivalent Presentation of Carbohydrates

Zitieren

Dateien zu dieser Ressource

Prüfsumme: MD5:3afe61adb528e24c9c5e0e1a937b305f

WITTMANN, Valentin, Sonja SEEBERGER, 2001. Spatial Screening of Lectin Ligands : Cyclic Peptides as Scaffolds for Multivalent Presentation of Carbohydrates. In: LEBL, Michal, ed.. Peptides : the wave of the future : 2nd International Peptide Symposium, 17th American Peptide Symposium, San Diego, California, June 9-14, 2001. San Diego, Calif.:American Peptide Society, pp. 174-176

@inproceedings{Wittmann2001Spati-10018, title={Spatial Screening of Lectin Ligands : Cyclic Peptides as Scaffolds for Multivalent Presentation of Carbohydrates}, year={2001}, address={San Diego, Calif.}, publisher={American Peptide Society}, booktitle={Peptides : the wave of the future : 2nd International Peptide Symposium, 17th American Peptide Symposium, San Diego, California, June 9-14, 2001}, pages={174--176}, editor={Lebl, Michal}, author={Wittmann, Valentin and Seeberger, Sonja} }

<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#" xmlns:foaf="http://xmlns.com/foaf/0.1/" xmlns:void="http://rdfs.org/ns/void#" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/10018"> <dc:creator>Seeberger, Sonja</dc:creator> <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/29"/> <dcterms:rights rdf:resource="https://creativecommons.org/licenses/by-nc-nd/2.0/legalcode"/> <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/> <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/10018"/> <dc:rights>deposit-license</dc:rights> <dc:contributor>Seeberger, Sonja</dc:contributor> <dc:creator>Wittmann, Valentin</dc:creator> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-24T18:16:00Z</dcterms:available> <dcterms:title>Spatial Screening of Lectin Ligands : Cyclic Peptides as Scaffolds for Multivalent Presentation of Carbohydrates</dcterms:title> <dcterms:abstract xml:lang="eng">Carbohydrate-lectin interactions are the basis of numerous biologically important recognition processes. Examples include the initiation of the inflammatory response, bacterial and viral pathogenesis, fertilization, and even protein folding. High-affinity lectin ligands are of considerable medicinal interest in the diagnosis, therapy, and prevention of conditions associated with these processes. One approach to arrive at such ligands is the design of small oligovalent carbohydrate derivatives (mini clusters) which can simultaneously bind to several binding sites of a single (oligomeric) lectin proximate in space and may be tailored to lectins with known 3D-structure ( directed multivalency). However, if the structure of the targeted lectin and thus the required orientation of the sugar epitopes of the mini clusters are unknown, an efficient procedure for the generation and screening of libraries of spatially diverse mini clusters is desirable. Here we present a new strategy for finding multivalent lectin ligands by spatial screening using libraries of cyclic peptides as scaffolds for multivalent presentation of carbohydrate epitopes.</dcterms:abstract> <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/29"/> <foaf:homepage rdf:resource="http://localhost:8080/jspui"/> <dcterms:bibliographicCitation>First publ. in: Peptides: the wave of the future / 2nd International Peptide Symposium, 17th American Peptide Symposium, San Diego, California, June 9-14, 2001. Michal Lebl (ed.). - San Diego, Calif.: American Peptide Society, 2001, pp. 174-176</dcterms:bibliographicCitation> <dcterms:issued>2001</dcterms:issued> <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/10018/1/witt_019.pdf"/> <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/10018/1/witt_019.pdf"/> <dc:language>eng</dc:language> <dc:contributor>Wittmann, Valentin</dc:contributor> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-24T18:16:00Z</dc:date> <dc:format>application/pdf</dc:format> </rdf:Description> </rdf:RDF>

Dateiabrufe seit 01.10.2014 (Informationen über die Zugriffsstatistik)

witt_019.pdf 115

Das Dokument erscheint in:

deposit-license Solange nicht anders angezeigt, wird die Lizenz wie folgt beschrieben: deposit-license

KOPS Suche


Stöbern

Mein Benutzerkonto