Poly(ADP-ribose) polymerase-1, DNA repair and mammalian longevity

Kurzanzeige
dc.contributor.authorBürkle, Alexander
dc.contributor.authorBeneke, Sascha
dc.contributor.authorBrabeck, Christine
dc.contributor.authorLeake, Alan
dc.contributor.authorMeyer, Ralph
dc.contributor.authorMuiras, Marie-Laure
dc.contributor.authorPfeiffer, Ragen
dc.date.accessioned2020-12-17T13:23:38Z
dc.date.available2020-12-17T13:23:38Z
dc.date.issued2002eng
dc.description.abstractCellular DNA repair activities can be expected to control the rate of the ageing process by keeping the steady-state levels of DNA damage, which is continuously induced by endogenous and exogenous damaging agents, at low levels. Poly(ADP-ribosyl)ation is one of the immediate biochemical reactions of eukaryotic cells to DNA damage and is functionally associated with DNA base-excision repair and strand break repair. Here we review the current state of the art concerning the relationship between DNA strand break repair, poly(ADP-ribosyl)ation, maintenance of genomic stability and mammalian life span.eng
dc.description.versionpublishedeng
dc.identifier.doi10.1016/S0531-5565(02)00144-4eng
dc.identifier.urihttps://kops.uni-konstanz.de/handle/123456789/52162
dc.language.isoengeng
dc.rightsterms-of-use
dc.rights.urihttps://rightsstatements.org/page/InC/1.0/
dc.subjectAgeing, Longevity Poly(ADP-ribose) polymerase-1, DNA base-excision repair, Genomic instabilityeng
dc.subject.ddc570eng
dc.titlePoly(ADP-ribose) polymerase-1, DNA repair and mammalian longevityeng
dc.typeJOURNAL_ARTICLEeng
dspace.entity.typePublication
kops.citation.bibtex
@article{Burkle2002PolyA-52162,
  year={2002},
  doi={10.1016/S0531-5565(02)00144-4},
  title={Poly(ADP-ribose) polymerase-1, DNA repair and mammalian longevity},
  number={10-11},
  volume={37},
  issn={0531-5565},
  journal={Experimental Gerontology},
  pages={1203--1205},
  author={Bürkle, Alexander and Beneke, Sascha and Brabeck, Christine and Leake, Alan and Meyer, Ralph and Muiras, Marie-Laure and Pfeiffer, Ragen}
}
kops.citation.iso690BÜRKLE, Alexander, Sascha BENEKE, Christine BRABECK, Alan LEAKE, Ralph MEYER, Marie-Laure MUIRAS, Ragen PFEIFFER, 2002. Poly(ADP-ribose) polymerase-1, DNA repair and mammalian longevity. In: Experimental Gerontology. Elsevier. 2002, 37(10-11), pp. 1203-1205. ISSN 0531-5565. eISSN 1873-6815. Available under: doi: 10.1016/S0531-5565(02)00144-4deu
kops.citation.iso690BÜRKLE, Alexander, Sascha BENEKE, Christine BRABECK, Alan LEAKE, Ralph MEYER, Marie-Laure MUIRAS, Ragen PFEIFFER, 2002. Poly(ADP-ribose) polymerase-1, DNA repair and mammalian longevity. In: Experimental Gerontology. Elsevier. 2002, 37(10-11), pp. 1203-1205. ISSN 0531-5565. eISSN 1873-6815. Available under: doi: 10.1016/S0531-5565(02)00144-4eng
kops.citation.rdf
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/52162">
    <dc:creator>Meyer, Ralph</dc:creator>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2020-12-17T13:23:38Z</dc:date>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2020-12-17T13:23:38Z</dcterms:available>
    <dc:contributor>Meyer, Ralph</dc:contributor>
    <dc:creator>Beneke, Sascha</dc:creator>
    <dc:language>eng</dc:language>
    <dcterms:rights rdf:resource="https://rightsstatements.org/page/InC/1.0/"/>
    <dc:creator>Leake, Alan</dc:creator>
    <dc:creator>Pfeiffer, Ragen</dc:creator>
    <dc:creator>Brabeck, Christine</dc:creator>
    <dcterms:abstract xml:lang="eng">Cellular DNA repair activities can be expected to control the rate of the ageing process by keeping the steady-state levels of DNA damage, which is continuously induced by endogenous and exogenous damaging agents, at low levels. Poly(ADP-ribosyl)ation is one of the immediate biochemical reactions of eukaryotic cells to DNA damage and is functionally associated with DNA base-excision repair and strand break repair. Here we review the current state of the art concerning the relationship between DNA strand break repair, poly(ADP-ribosyl)ation, maintenance of genomic stability and mammalian life span.</dcterms:abstract>
    <dc:contributor>Brabeck, Christine</dc:contributor>
    <dc:contributor>Leake, Alan</dc:contributor>
    <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/52162"/>
    <dc:creator>Muiras, Marie-Laure</dc:creator>
    <dc:contributor>Muiras, Marie-Laure</dc:contributor>
    <dc:creator>Bürkle, Alexander</dc:creator>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dc:contributor>Beneke, Sascha</dc:contributor>
    <dcterms:title>Poly(ADP-ribose) polymerase-1, DNA repair and mammalian longevity</dcterms:title>
    <dc:contributor>Bürkle, Alexander</dc:contributor>
    <dc:contributor>Pfeiffer, Ragen</dc:contributor>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dcterms:issued>2002</dcterms:issued>
    <dc:rights>terms-of-use</dc:rights>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
  </rdf:Description>
</rdf:RDF>
kops.flag.isPeerReviewedtrueeng
kops.flag.knbibliographyfalse
kops.sourcefieldExperimental Gerontology. Elsevier. 2002, <b>37</b>(10-11), pp. 1203-1205. ISSN 0531-5565. eISSN 1873-6815. Available under: doi: 10.1016/S0531-5565(02)00144-4deu
kops.sourcefield.plainExperimental Gerontology. Elsevier. 2002, 37(10-11), pp. 1203-1205. ISSN 0531-5565. eISSN 1873-6815. Available under: doi: 10.1016/S0531-5565(02)00144-4deu
kops.sourcefield.plainExperimental Gerontology. Elsevier. 2002, 37(10-11), pp. 1203-1205. ISSN 0531-5565. eISSN 1873-6815. Available under: doi: 10.1016/S0531-5565(02)00144-4eng
relation.isAuthorOfPublication99f10fd7-72b9-483a-9c91-e43d378c52d0
relation.isAuthorOfPublicationb1afc9e3-ff8f-4e83-86b0-400310a75628
relation.isAuthorOfPublication.latestForDiscovery99f10fd7-72b9-483a-9c91-e43d378c52d0
source.bibliographicInfo.fromPage1203eng
source.bibliographicInfo.issue10-11eng
source.bibliographicInfo.toPage1205eng
source.bibliographicInfo.volume37eng
source.identifier.eissn1873-6815eng
source.identifier.issn0531-5565eng
source.periodicalTitleExperimental Gerontologyeng
source.publisherElseviereng

Dateien

Sammlungen

Biologie: Publikationen