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Brief communication: coagulation profiles of HIV positive patients on antiretroviral therapy (ART) at the Mampong Municipal Hospital, Ashanti-Region, Ghana : a case control study

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Datum

2024

Autor:innen

Opoku, Freddie Boateng
Yalley, Akua Koaso
Nii-Trebi, Nicholas Israel
Kyeremeh, Ransford

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AIDS Research and Therapy. Springer. 2024, 21, 72. eISSN 1742-6405. Verfügbar unter: doi: 10.1186/s12981-024-00665-w

Zusammenfassung

This study aimed to ascertain how the current two ART regimens used in Ghana affected HIV patients’ coagulation profiles. A case-control study was conducted on 102 HIV positive patients at the Mampong Municipal Hospital. Coagulation parameters measured showed APTT was normal in majority of ART-experienced participants but prolonged in majority of ART-naïve participants. The mean platelet count was significantly higher in ART-experienced participants. No significant differences were found between the coagulation profiles of ART-experienced patients on two different drug regimens. In conclusion, current ART can enhance the coagulation profiles in HIV-infected patients, by improving platelet count and APTT.

Zusammenfassung in einer weiteren Sprache

Fachgebiet (DDC)
320 Politik

Schlagwörter

Antiretroviral therapy, Human immunodeficiency virus, Coagulation profile, Activated partial thromboplastin time, Platelet count, International normalized ratio

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ISO 690OPOKU, Freddie Boateng, Akua Koaso YALLEY, Nicholas Israel NII-TREBI, Ekoutiame Ahlonkor AHLIN, Abena Asefuaba YALLEY, Ransford KYEREMEH, 2024. Brief communication: coagulation profiles of HIV positive patients on antiretroviral therapy (ART) at the Mampong Municipal Hospital, Ashanti-Region, Ghana : a case control study. In: AIDS Research and Therapy. Springer. 2024, 21, 72. eISSN 1742-6405. Verfügbar unter: doi: 10.1186/s12981-024-00665-w
BibTex
@article{Opoku2024-10-22Brief-71985,
  title={Brief communication: coagulation profiles of HIV positive patients on antiretroviral therapy (ART) at the Mampong Municipal Hospital, Ashanti-Region, Ghana : a case control study},
  year={2024},
  doi={10.1186/s12981-024-00665-w},
  volume={21},
  journal={AIDS Research and Therapy},
  author={Opoku, Freddie Boateng and Yalley, Akua Koaso and Nii-Trebi, Nicholas Israel and Ahlin, Ekoutiame Ahlonkor and Yalley, Abena Asefuaba and Kyeremeh, Ransford},
  note={Article Number: 72}
}
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