Publikation: Behavioral sensitization to apomorphine in pigeons (Columba livia) : blockade by the D₁ dopamine antagonist SCH-23390
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2004
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Acerbo, Martin J.
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Behavioral Neuroscience. 2004, 118(5), pp. 1080-1088. ISSN 0735-7044. Available under: doi: 10.1037/0735-7044.118.5.1080
Zusammenfassung
Repeated administration of apomorphine leads to a context-dependent pecking response sensitization. Previously sensitized pigeons (Columba livia) challenged with saline in the same context show a conditioned response (CR). The authors studied the effects of intrastriatal injections of the dopamine (D₁) antagonist SCH-23390 on both the sensitized response and the CR. When coadministered with apomorphine, SCH-23390 inhibited the initial response to apomorphine, prevented the development of sensitization, and impaired the maintenance of an already developed sensitization. However, SCH-23390 had no effect on the retrieval of a previously established CR. It is concluded that the activation of D₁ receptors in the caudal avian striatum is necessary for the acquisition and maintenance of the sensitization, but not for the expression, of the CR.
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150 Psychologie
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ACERBO, Martin J., Juan DELIUS, 2004. Behavioral sensitization to apomorphine in pigeons (Columba livia) : blockade by the D₁ dopamine antagonist SCH-23390. In: Behavioral Neuroscience. 2004, 118(5), pp. 1080-1088. ISSN 0735-7044. Available under: doi: 10.1037/0735-7044.118.5.1080BibTex
@article{Acerbo2004-10Behav-20261,
year={2004},
doi={10.1037/0735-7044.118.5.1080},
title={Behavioral sensitization to apomorphine in pigeons (Columba livia) : blockade by the D₁ dopamine antagonist SCH-23390},
number={5},
volume={118},
issn={0735-7044},
journal={Behavioral Neuroscience},
pages={1080--1088},
author={Acerbo, Martin J. and Delius, Juan}
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