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Visualization and Analysis of a Cardio Vascular Diseaseand MUPP1-related Biological Network combining Text Mining and Data Warehouse Approaches

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Sommer_2-2tro85talstf3.pdf
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2010

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Tiys, Evgeny S.
Kormeier, Benjamin
Hippe, Klaus
Janowski, Sebastian J.
Ivanisenko, Timofey V.
Bragin, Anatoly O.
Arrigo, Patrizio
Demenkov, Pavel S.
Kochetov, Alexey V.
et al.

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Journal of Integrative Bioinformatics. 2010, 7(1), 148. eISSN 1613-4516. Available under: doi: 10.1515/jib-2010-148

Zusammenfassung

Detailed investigation of socially important diseases with modern experimental methods has resulted in the generation of large volume of valuable data. However, analysis and interpretation of this data needs application of efficient computational techniques and systems biology approaches. In particular, the techniques allowing the reconstruction of associative networks of various biological objects and events can be useful. In this publication, the combination of different techniques to create such a network associated with an abstract cell environment is discussed in order to gain insights into the functional as well as spatial interrelationships. It is shown that experimentally gained knowledge enriched with data warehouse content and text mining data can be used for the reconstruction and localization of a cardiovascular disease developing network beginning with MUPP1/MPDZ (multi-PDZ domain protein).

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ISO 690SOMMER, Björn, Evgeny S. TIYS, Benjamin KORMEIER, Klaus HIPPE, Sebastian J. JANOWSKI, Timofey V. IVANISENKO, Anatoly O. BRAGIN, Patrizio ARRIGO, Pavel S. DEMENKOV, Alexey V. KOCHETOV, 2010. Visualization and Analysis of a Cardio Vascular Diseaseand MUPP1-related Biological Network combining Text Mining and Data Warehouse Approaches. In: Journal of Integrative Bioinformatics. 2010, 7(1), 148. eISSN 1613-4516. Available under: doi: 10.1515/jib-2010-148
BibTex
@article{Sommer2010-03-01Visua-44741,
  year={2010},
  doi={10.1515/jib-2010-148},
  title={Visualization and Analysis of a Cardio Vascular Diseaseand MUPP1-related Biological Network combining Text Mining and Data Warehouse Approaches},
  number={1},
  volume={7},
  journal={Journal of Integrative Bioinformatics},
  author={Sommer, Björn and Tiys, Evgeny S. and Kormeier, Benjamin and Hippe, Klaus and Janowski, Sebastian J. and Ivanisenko, Timofey V. and Bragin, Anatoly O. and Arrigo, Patrizio and Demenkov, Pavel S. and Kochetov, Alexey V.},
  note={Article Number: 148}
}
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