Publikation:

Development of a β-C–H Bromination Approach toward the Synthesis of Jerantinine E

Vorschaubild

Dateien

Zu diesem Dokument gibt es keine Dateien.

Datum

2017

Autor:innen

Huber, Tatjana
Preuhs, Teresa A.
Magauer, Thomas

Herausgeber:innen

Kontakt

ISSN der Zeitschrift

Electronic ISSN

ISBN

Bibliografische Daten

Verlag

Schriftenreihe

Auflagebezeichnung

URI (zitierfähiger Link)
DOI (zitierfähiger Link)
https://doi.org/10.1021/acs.joc.7b01095
ArXiv-ID

Internationale Patentnummer

Angaben zur Forschungsförderung

Projekt

Open Access-Veröffentlichung

Sammlungen

Chemie: Publikationen
Core Facility der Universität Konstanz

Gesperrt bis

Titel in einer weiteren Sprache

Publikationstyp
Zeitschriftenartikel
Publikationsstatus
Published

Erschienen in

The Journal of Organic Chemistry. 2017, 82(14), pp. 7410-7419. ISSN 0022-3263. eISSN 1520-6904. Available under: doi: 10.1021/acs.joc.7b01095

Zusammenfassung

The development of an asymmetric and highly convergent three-component synthesis of the functionalized ABC ring system of the Aspidosperma alkaloid jerantinine E is reported. The presented synthetic strategy relies on our recently developed method for the one-pot β-C-H bromination of enones, which allows for rapid construction of the tricyclic tetrahydrocarbazolone core via a palladium-catalyzed amination and oxidative indole formation. Moreover, a secondary amine building block that contains all carbon atoms of the D and E ring of the natural product could be installed in three additional steps.

Zusammenfassung in einer weiteren Sprache

Fachgebiet (DDC)
540 Chemie

Schlagwörter

Konferenz

Rezension
undefined / . - undefined, undefined

Forschungsvorhaben

Organisationseinheiten

Zeitschriftenheft

Zugehörige Datensätze in KOPS

Zitieren

ISO 690HUBER, Tatjana, Teresa A. PREUHS, Christa K. G. GERLINGER, Thomas MAGAUER, 2017. Development of a β-C–H Bromination Approach toward the Synthesis of Jerantinine E. In: The Journal of Organic Chemistry. 2017, 82(14), pp. 7410-7419. ISSN 0022-3263. eISSN 1520-6904. Available under: doi: 10.1021/acs.joc.7b01095
BibTex
@article{Huber2017Devel-40514,
  year={2017},
  doi={10.1021/acs.joc.7b01095},
  title={Development of a β-C–H Bromination Approach toward the Synthesis of Jerantinine E},
  number={14},
  volume={82},
  issn={0022-3263},
  journal={The Journal of Organic Chemistry},
  pages={7410--7419},
  author={Huber, Tatjana and Preuhs, Teresa A. and Gerlinger, Christa K. G. and Magauer, Thomas}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/40514">
    <dc:creator>Preuhs, Teresa A.</dc:creator>
    <dcterms:title>Development of a β-C–H Bromination Approach toward the Synthesis of Jerantinine E</dcterms:title>
    <dcterms:issued>2017</dcterms:issued>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dc:creator>Magauer, Thomas</dc:creator>
    <dc:contributor>Preuhs, Teresa A.</dc:contributor>
    <dc:contributor>Magauer, Thomas</dc:contributor>
    <dcterms:abstract xml:lang="eng">The development of an asymmetric and highly convergent three-component synthesis of the functionalized ABC ring system of the Aspidosperma alkaloid jerantinine E is reported. The presented synthetic strategy relies on our recently developed method for the one-pot β-C-H bromination of enones, which allows for rapid construction of the tricyclic tetrahydrocarbazolone core via a palladium-catalyzed amination and oxidative indole formation. Moreover, a secondary amine building block that contains all carbon atoms of the D and E ring of the natural product could be installed in three additional steps.</dcterms:abstract>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-11-08T10:33:09Z</dc:date>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-11-08T10:33:09Z</dcterms:available>
    <dc:creator>Gerlinger, Christa K. G.</dc:creator>
    <dc:language>eng</dc:language>
    <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/40514"/>
    <dc:contributor>Huber, Tatjana</dc:contributor>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/29"/>
    <dc:creator>Huber, Tatjana</dc:creator>
    <dc:contributor>Gerlinger, Christa K. G.</dc:contributor>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/29"/>
  </rdf:Description>
</rdf:RDF>

Interner Vermerk

xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter

Kontakt
URL der Originalveröffentl.

Prüfdatum der URL

Prüfungsdatum der Dissertation

Finanzierungsart

Kommentar zur Publikation

Allianzlizenz
Corresponding Authors der Uni Konstanz vorhanden
Internationale Co-Autor:innen
Universitätsbibliographie
Ja
Begutachtet
Diese Publikation teilen