Publikation:

Effective behavioral treatment of focal hand dystonia in musicians alters somatosensory cortical organization

Lade...
Vorschaubild

Dateien

Candia_et_al_PNAS03_PNAS.pdf
Candia_et_al_PNAS03_PNAS.pdfGröße: 160.18 KBDownloads: 273

Datum

2003

Autor:innen

Herausgeber:innen

Kontakt

ISSN der Zeitschrift

Electronic ISSN

ISBN

Bibliografische Daten

Verlag

Schriftenreihe

Auflagebezeichnung

ArXiv-ID

Internationale Patentnummer

Angaben zur Forschungsförderung

Projekt

Open Access-Veröffentlichung
Open Access Green
Core Facility der Universität Konstanz

Gesperrt bis

Titel in einer weiteren Sprache

Publikationstyp
Zeitschriftenartikel
Publikationsstatus
Published

Erschienen in

PNAS. 2003, 100, pp. 7942-7946. Available under: doi: 10.1073/pnas.1231193100

Zusammenfassung

New perspectives in neurorehabilitation suggest that behavioral treatments of movement disorders may modify the functional organization of central somatosensory neural networks. On the basis of the assumption that use-dependent reorganization in these networks contributes to the fundamental abnormalities seen in focal dystonia, we treated 10 affected musicians and measured the concomitant somatosensory changes by using whole-head magnetoencephalography. We found that effective treatment, using the method of sensory motor retuning, leads to alterations in the functional organization of the somatosensory cortex. Specifically, before treatment, somatosensory relationships of the individual fingers differ between the affected and unaffected hands, whereas after treatment, finger representations contralateral to the dystonic side become more similar to the less-affected side. Further, somatosensory finger representations are ordered more according to homuncular principles after treatment. In addition, the observed physiologic changes correlated with behavioral data. These results confirm that plastic changes in parallel with emergent neurological dysfunction may be reversed by context-specific, intensive training-based remediation.

Zusammenfassung in einer weiteren Sprache

Fachgebiet (DDC)
150 Psychologie

Schlagwörter

neuroscience

Konferenz

Rezension
undefined / . - undefined, undefined

Forschungsvorhaben

Organisationseinheiten

Zeitschriftenheft

Zugehörige Datensätze in KOPS

Zitieren

ISO 690CANDIA, Victor, Christian WIENBRUCH, Thomas ELBERT, Brigitte ROCKSTROH, William RAY, 2003. Effective behavioral treatment of focal hand dystonia in musicians alters somatosensory cortical organization. In: PNAS. 2003, 100, pp. 7942-7946. Available under: doi: 10.1073/pnas.1231193100
BibTex
@article{Candia2003Effec-10985,
  year={2003},
  doi={10.1073/pnas.1231193100},
  title={Effective behavioral treatment of focal hand dystonia in musicians alters somatosensory cortical organization},
  volume={100},
  journal={PNAS},
  pages={7942--7946},
  author={Candia, Victor and Wienbruch, Christian and Elbert, Thomas and Rockstroh, Brigitte and Ray, William}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/10985">
    <dc:contributor>Rockstroh, Brigitte</dc:contributor>
    <dc:language>eng</dc:language>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/43"/>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-25T09:24:29Z</dc:date>
    <dc:creator>Elbert, Thomas</dc:creator>
    <dcterms:abstract xml:lang="eng">New perspectives in neurorehabilitation suggest that behavioral treatments of movement disorders may modify the functional organization of central somatosensory neural networks. On the basis of the assumption that use-dependent reorganization in these networks contributes to the fundamental abnormalities seen in focal dystonia, we treated 10 affected musicians and  measured the concomitant somatosensory changes by using whole-head  magnetoencephalography. We found that effective treatment, using the method of sensory motor retuning, leads to alterations in the functional organization of the somatosensory cortex. Specifically, before treatment, somatosensory relationships of the individual fingers differ between the affected and unaffected hands, whereas after treatment, finger representations contralateral to the dystonic side become more similar to the less-affected  side. Further, somatosensory finger representations are ordered more according to homuncular principles after treatment. In addition, the observed physiologic changes correlated with behavioral data. These results confirm that plastic changes in parallel with emergent neurological dysfunction may be reversed by context-specific, intensive training-based remediation.</dcterms:abstract>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/43"/>
    <dc:creator>Ray, William</dc:creator>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-25T09:24:29Z</dcterms:available>
    <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/10985/1/Candia_et_al_PNAS03_PNAS.pdf"/>
    <dcterms:issued>2003</dcterms:issued>
    <dc:creator>Candia, Victor</dc:creator>
    <dcterms:rights rdf:resource="https://rightsstatements.org/page/InC/1.0/"/>
    <dc:creator>Wienbruch, Christian</dc:creator>
    <dc:contributor>Ray, William</dc:contributor>
    <dc:contributor>Elbert, Thomas</dc:contributor>
    <dc:rights>terms-of-use</dc:rights>
    <dc:format>application/pdf</dc:format>
    <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/10985"/>
    <dc:creator>Rockstroh, Brigitte</dc:creator>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dc:contributor>Candia, Victor</dc:contributor>
    <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/10985/1/Candia_et_al_PNAS03_PNAS.pdf"/>
    <dc:contributor>Wienbruch, Christian</dc:contributor>
    <dcterms:bibliographicCitation>First publ. in: PNAS 2003 100: 7942-7946</dcterms:bibliographicCitation>
    <dcterms:title>Effective behavioral treatment of focal hand dystonia in musicians alters somatosensory cortical organization</dcterms:title>
  </rdf:Description>
</rdf:RDF>

Interner Vermerk

xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter

Kontakt
URL der Originalveröffentl.

Prüfdatum der URL

Prüfungsdatum der Dissertation

Finanzierungsart

Kommentar zur Publikation

Allianzlizenz
Corresponding Authors der Uni Konstanz vorhanden
Internationale Co-Autor:innen
Universitätsbibliographie
Ja
Begutachtet
Diese Publikation teilen