Publikation:

Bias against disconfirmatory evidence in the 'at-risk mental state' and during psychosis

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2016

Autor:innen

Eisenacher, Sarah
Rausch, Franziska
Fenske, Sabrina
Veckenstedt, Ruth
Englisch, Susanne
Andreou, Christina
Moritz, Steffen
Meyer-Lindenberg, Andreas
et al.

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http://nbn-resolving.de/urn:nbn:de:bsz:352-2-7preoyknbnvc7
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https://doi.org/10.1016/j.psychres.2016.02.028
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Psychologie: Publikationen
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Published

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Psychiatry research. 2016, 238, pp. 242-250. ISSN 0165-1781. eISSN 1872-7123. Available under: doi: 10.1016/j.psychres.2016.02.028

Zusammenfassung

Prior studies have confirmed a bias against disconfirmatory evidence (BADE) in schizophrenia which has been associated with delusions. However, its role in the pathogenesis of psychosis is yet unclear. The objective was to investigate BADE for the first time in subjects with an at-risk-mental-state for psychosis (ARMS), patients with a first episode of psychosis without antipsychotic treatment (FEP) and healthy controls (HC). A standard BADE test presenting written scenarios was employed. In addition, psychometric rating scales and a neuropsychological test battery were applied. A three-staged image was revealed. FEP-patients showed a significant BADE compared to the other groups. The performance of ARMS-patients lay in between HC and FEP-patients. A trend towards significance became evident for a bias against confirmatory evidence (BACE) in FEP-patients. Results were not attributable to antipsychotic or other medication or depressive symptoms. Correlations with delusions reached medium effect sizes but failed significance after Bonferroni-corrections. These results provide evidence for aberrations in evidence integration in the pathogenesis of psychosis and contribute to our knowledge of metacognitive functioning which can be used for (meta-)cognitive intervention in psychosis.

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150 Psychologie

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ISO 690EISENACHER, Sarah, Franziska RAUSCH, Daniela MIER, Sabrina FENSKE, Ruth VECKENSTEDT, Susanne ENGLISCH, Anna BECKER, Christina ANDREOU, Steffen MORITZ, Andreas MEYER-LINDENBERG, 2016. Bias against disconfirmatory evidence in the 'at-risk mental state' and during psychosis. In: Psychiatry research. 2016, 238, pp. 242-250. ISSN 0165-1781. eISSN 1872-7123. Available under: doi: 10.1016/j.psychres.2016.02.028
BibTex
@article{Eisenacher2016-04-30again-45236,
  year={2016},
  doi={10.1016/j.psychres.2016.02.028},
  title={Bias against disconfirmatory evidence in the 'at-risk mental state' and during psychosis},
  volume={238},
  issn={0165-1781},
  journal={Psychiatry research},
  pages={242--250},
  author={Eisenacher, Sarah and Rausch, Franziska and Mier, Daniela and Fenske, Sabrina and Veckenstedt, Ruth and Englisch, Susanne and Becker, Anna and Andreou, Christina and Moritz, Steffen and Meyer-Lindenberg, Andreas}
}
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