Khat abuse as risk factor for development of psychotic symptoms in trauma patients : a feasibility study for further genetico-epidemiological studies in the GGFRC, ethiopia
Khat abuse as risk factor for development of psychotic symptoms in trauma patients : a feasibility study for further genetico-epidemiological studies in the GGFRC, ethiopia
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Date
2017
Authors
Adorjan, Kristina
Tesfaye, Markos
Tessema, Fasil
Toennes, Stefan
Suleman, Sultan
Susser, Ezra
Papiol, Sergi
Soboka, Matiwos
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Abstracts of the XXIV World Congress of Psychiatric Genetics (WCPG). - Amsterdam : Elsevier, 2017. - (European Neuropsychopharmacology ; 27, Suppl 3). - pp. S468. - ISSN 0924-977X. - eISSN 1873-7862
Abstract
The Jimma University in southwestern Ethiopia has a unique health and demographic surveillance system called „Gilgel Gibe Field Research Center” (GGFRC) with a catchment area of about 50.000 people. In this setting, we studied the effect of khat use as risk factor for the development and the stability of psychotic symptoms among young men in the community. Our aim was to validate pilot data by testing the hypothesis, whether objective biological data on khat abuse are related in a meaningful way to behavioral self-reports of study participants and psychiatric symptom presentation assessed by trained interviewers. We assumed that khat alkaloids in urine samples of respondents are related to a higher probability of psychotic symptom presentation, especially in the subgroup with high trauma load. Furthermore, we wanted to demonstrate the reliability and validity of research methods that are necessary for future genetic epidemiological studies, i.e. the validity and reliability of pharmacological screening tests as well as assessments performed by trained local interviewers.
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150 Psychology
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XXIV World Congress of Psychiatric Genetics (WCPG), Oct 30, 2016 - Nov 4, 2016, Jerusalem, Israel
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ADORJAN, Kristina, Marina WIDMANN, Markos TESFAYE, Fasil TESSEMA, Stefan TOENNES, Sultan SULEMAN, Ezra SUSSER, Sergi PAPIOL, Matiwos SOBOKA, Michael ODENWALD, 2017. Khat abuse as risk factor for development of psychotic symptoms in trauma patients : a feasibility study for further genetico-epidemiological studies in the GGFRC, ethiopia. XXIV World Congress of Psychiatric Genetics (WCPG). Jerusalem, Israel, Oct 30, 2016 - Nov 4, 2016. In: Abstracts of the XXIV World Congress of Psychiatric Genetics (WCPG). Amsterdam:Elsevier, pp. S468. ISSN 0924-977X. eISSN 1873-7862. Available under: doi: 10.1016/j.euroneuro.2016.09.545BibTex
@inproceedings{Adorjan2017abuse-41385, year={2017}, doi={10.1016/j.euroneuro.2016.09.545}, title={Khat abuse as risk factor for development of psychotic symptoms in trauma patients : a feasibility study for further genetico-epidemiological studies in the GGFRC, ethiopia}, number={27, Suppl 3}, issn={0924-977X}, publisher={Elsevier}, address={Amsterdam}, series={European Neuropsychopharmacology}, booktitle={Abstracts of the XXIV World Congress of Psychiatric Genetics (WCPG)}, author={Adorjan, Kristina and Widmann, Marina and Tesfaye, Markos and Tessema, Fasil and Toennes, Stefan and Suleman, Sultan and Susser, Ezra and Papiol, Sergi and Soboka, Matiwos and Odenwald, Michael} }
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