@article{Stokes2022-08-14Assoc-55662,
  year={2022},
  doi={10.1017/S0007114521004633},
  title={Association between fat-soluble vitamins and self-reported health status : a cross-sectional analysis of the MARK-AGE cohort},
  number={3},
  volume={128},
  issn={0007-1145},
  journal={British Journal of Nutrition (BJN)},
  pages={433--443},
  author={Stokes, Caroline S. and Weber, Daniela and Wagenpfeil, Stefan and Stuetz, Wolfgang and Moreno-Villanueva, Maria and Dollé, Martijn E. T. and Jansen, Eugène and Gonos, Efstathios S. and Bernhardt, Jürgen and Bürkle, Alexander}
}

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    <dc:creator>Moreno-Villanueva, Maria</dc:creator>
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    <dc:creator>Gonos, Efstathios S.</dc:creator>
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    <dc:contributor>Stokes, Caroline S.</dc:contributor>
    <dc:creator>Bernhardt, Jürgen</dc:creator>
    <dc:contributor>Jansen, Eugène</dc:contributor>
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    <dc:creator>Jansen, Eugène</dc:creator>
    <dcterms:abstract xml:lang="eng">Self-rated health (SRH) is associated with higher risk of death. Since low plasma levels of fat-soluble vitamins are related to mortality, we aimed to assess whether plasma concentrations of vitamins A, D and E were associated with SRH in the MARK-AGE study. We included 3158 participants (52% female) aged between 35-75 years. Cross-sectional data were collected via questionnaires. An enzyme immunoassay quantified 25-hydroxyvitamin D and HPLC determined α-tocopherol and retinol plasma concentrations. The median 25-hydroxyvitamin D and retinol concentrations differed significantly (P&lt;0.001) between SRH categories, and were lower in the combined fair/poor category versus the excellent, very good, good categories (25-hydroxvitamin D: 40.8 vs. 51.9, 49.3, 46.7 nmol/l, respectively; retinol: 1.67 vs. 1.75, 1.74, 1.70 µmol/l, respectively). Both vitamin D and retinol status were independently associated with fair/poor SRH in multiple regression analyses: adjusted ORs (95% CI) for the vitamin D insufficiency, deficiency, severe deficiency categories were 1.33 (1.06-1.68), 1.50 (1.17-1.93), and 1.83 (1.34-2.50) respectively; P=0.015, P=0.001, P&lt;0.001, and for the second/third/fourth retinol quartiles: 1.44 (1.18-1.75), 1.57 (1.28-1.93), 1.49 (1.20-1.84); all P&lt;0.001. No significant associations were reported for α-tocopherol quartiles. Lower vitamin A and D status emerged as independent markers for fair/poor SRH. Further insights into the long-term implications of these modifiable nutrients on health status are warranted.</dcterms:abstract>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2021-11-25T14:19:24Z</dcterms:available>
    <dc:contributor>Dollé, Martijn E. T.</dc:contributor>
    <dc:contributor>Weber, Daniela</dc:contributor>
    <dc:creator>Dollé, Martijn E. T.</dc:creator>
    <dc:contributor>Moreno-Villanueva, Maria</dc:contributor>
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    <dc:contributor>Wagenpfeil, Stefan</dc:contributor>
    <dc:contributor>Stuetz, Wolfgang</dc:contributor>
    <dc:creator>Bürkle, Alexander</dc:creator>
    <dc:rights>terms-of-use</dc:rights>
    <dcterms:issued>2022-08-14</dcterms:issued>
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    <dc:creator>Wagenpfeil, Stefan</dc:creator>
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    <dc:contributor>Bernhardt, Jürgen</dc:contributor>
    <dcterms:title>Association between fat-soluble vitamins and self-reported health status : a cross-sectional analysis of the MARK-AGE cohort</dcterms:title>
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    <dc:language>eng</dc:language>
    <dc:creator>Stuetz, Wolfgang</dc:creator>
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    <dc:contributor>Bürkle, Alexander</dc:contributor>
    <dc:contributor>Gonos, Efstathios S.</dc:contributor>
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