The neural dynamics of deficient memory control in heavily traumatized refugees

Kurzanzeige
dc.contributor.authorWaldhauser, Gerd T.
dc.contributor.authorDahl, Martin
dc.contributor.authorRuf-Leuschner, Martina
dc.contributor.authorMüller, Veronika
dc.contributor.authorSchauer, Maggie
dc.contributor.authorAxmacher, Nikolai
dc.contributor.authorElbert, Thomas
dc.contributor.authorHanslmayr, Simon
dc.date.accessioned2018-10-10T07:50:39Z
dc.date.available2018-10-10T07:50:39Z
dc.date.issued2018-09-03eng
dc.description.abstractVictims of war, torture and natural catastrophes are prone to develop posttraumatic stress disorder (PTSD). These individuals experience the recurrent, involuntary intrusion of traumatic memories. What neurocognitive mechanisms are driving this memory disorder? Here we show that PTSD symptoms in heavily traumatized refugees are related to deficits in the effective control of memory retrieval. In a think/no-think task, PTSD patients were unable to forget memories that they had previously tried to suppress when compared to control participants with the same trauma history but without PTSD. Deficits in voluntary forgetting were clinically relevant since they correlated with memory intrusions in everyday life. Magnetoencephalography (MEG) recorded during suppression attempts revealed that PTSD patients were unable to downregulate signatures of sensory long-term memory traces in the gamma frequency band (70-120 Hz). Thus, our data suggest that the inability to suppress unwanted memories through modulation of gamma activity is related to PTSD symptom severity.eng
dc.description.versionpublishedeng
dc.identifier.doi10.1038/s41598-018-31400-xeng
dc.identifier.pmid30177846eng
dc.identifier.ppn511707614
dc.identifier.urihttps://kops.uni-konstanz.de/handle/123456789/43468
dc.language.isoengeng
dc.rightsAttribution 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subject.ddc150eng
dc.titleThe neural dynamics of deficient memory control in heavily traumatized refugeeseng
dc.typeJOURNAL_ARTICLEeng
dspace.entity.typePublication
kops.citation.bibtex
@article{Waldhauser2018-09-03neura-43468,
  year={2018},
  doi={10.1038/s41598-018-31400-x},
  title={The neural dynamics of deficient memory control in heavily traumatized refugees},
  volume={8},
  journal={Scientific reports},
  author={Waldhauser, Gerd T. and Dahl, Martin and Ruf-Leuschner, Martina and Müller, Veronika and Schauer, Maggie and Axmacher, Nikolai and Elbert, Thomas and Hanslmayr, Simon},
  note={Article Number: 13132}
}
kops.citation.iso690WALDHAUSER, Gerd T., Martin DAHL, Martina RUF-LEUSCHNER, Veronika MÜLLER, Maggie SCHAUER, Nikolai AXMACHER, Thomas ELBERT, Simon HANSLMAYR, 2018. The neural dynamics of deficient memory control in heavily traumatized refugees. In: Scientific reports. 2018, 8, 13132. eISSN 2045-2322. Available under: doi: 10.1038/s41598-018-31400-xdeu
kops.citation.iso690WALDHAUSER, Gerd T., Martin DAHL, Martina RUF-LEUSCHNER, Veronika MÜLLER, Maggie SCHAUER, Nikolai AXMACHER, Thomas ELBERT, Simon HANSLMAYR, 2018. The neural dynamics of deficient memory control in heavily traumatized refugees. In: Scientific reports. 2018, 8, 13132. eISSN 2045-2322. Available under: doi: 10.1038/s41598-018-31400-xeng
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kops.relation.uniknProjectTitleMemo TV - Epigenetic, neural and cognitive memories of traumatic stress and violence
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