Differentiating anticipatory from reactive cortisol responses to psychosocial stress

No Thumbnail Available
Files
There are no files associated with this item.
Date
2013
Authors
Engert, Veronika
Efanov, Simona I.
Duchesne, Annie
Vogel, Susanne
Corbo, Vincent
Editors
Contact
Journal ISSN
Electronic ISSN
ISBN
Bibliographical data
Publisher
Series
URI (citable link)
ArXiv-ID
International patent number
Link to the license
oops
EU project number
Project
Open Access publication
Collections
Restricted until
Title in another language
Research Projects
Organizational Units
Journal Issue
Publication type
Journal article
Publication status
Published
Published in
Psychoneuroendocrinology ; 38 (2013), 8. - pp. 1328-1337. - ISSN 0306-4530. - eISSN 1873-3360
Abstract
Most psychosocial stress studies assess the overall cortisol response without further identifying the temporal dynamics within hormone levels. It has been shown, however, that the amplitude of anticipatory cortisol stress levels has a unique predictive value for psychological health. So far, no "best practice" in how to investigate the anticipatory cortisol stress response has emerged. The goal of the current research was to develop a protocol that would allow for a sensitive and easy-to-implement laboratory-based investigation into anticipatory cortisol stress levels. We initially tested 26 healthy men in either an anticipation- or stress-only condition of the Trier Social Stress Test (TSST) to map the distinct timelines of anticipatory and reactive cortisol release profiles (study 1). Subsequently, we administered the TSST to 50 healthy men such that the cortisol responses to anticipatory and reactive stress components could be dissociated (study 2). In both studies we sampled saliva cortisol at high frequency (at baseline, during 10min of anticipation and during and after 10min of acute stress) and the current mood state pre- and post-stress. We found anticipatory responder rates of 20% and 40%, with peak anticipatory cortisol levels between 14 and 20min after onset of anticipation. Visible changes in reactive cortisol levels occurred only after the termination of the acute stressor. We conclude that the best practice to detect a maximum number of anticipatory responders in the TSST would be to extend the anticipation phase to 15min. In doing so, the anticipatory cortisol peak could be captured at a time-point of the actual stressor that is uninfluenced by reactive cortisol levels. Overall, we could reveal several features of anticipatory responders. Most importantly, there was a positive correlation between anticipatory and reactive stress responses. There was no association between anticipatory cortisol and alpha-amylase as well as subjective-psychological stress responses. Future studies will have to determine whether the anticipatory responders differ with respect to various stress-sensitive parameters like sex, personality, psychological wellbeing or chronic stress.
Summary in another language
Subject (DDC)
150 Psychology
Keywords
Anticipatory stress; Cortisol; Alpha-amylase; Subjective–psychological stress response
Conference
Review
undefined / . - undefined, undefined. - (undefined; undefined)
Cite This
ISO 690ENGERT, Veronika, Simona I. EFANOV, Annie DUCHESNE, Susanne VOGEL, Vincent CORBO, Jens C. PRUESSNER, 2013. Differentiating anticipatory from reactive cortisol responses to psychosocial stress. In: Psychoneuroendocrinology. 38(8), pp. 1328-1337. ISSN 0306-4530. eISSN 1873-3360. Available under: doi: 10.1016/j.psyneuen.2012.11.018
BibTex
@article{Engert2013-08Diffe-38254,
  year={2013},
  doi={10.1016/j.psyneuen.2012.11.018},
  title={Differentiating anticipatory from reactive cortisol responses to psychosocial stress},
  number={8},
  volume={38},
  issn={0306-4530},
  journal={Psychoneuroendocrinology},
  pages={1328--1337},
  author={Engert, Veronika and Efanov, Simona I. and Duchesne, Annie and Vogel, Susanne and Corbo, Vincent and Pruessner, Jens C.}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/38254">
    <dcterms:abstract xml:lang="eng">Most psychosocial stress studies assess the overall cortisol response without further identifying the temporal dynamics within hormone levels. It has been shown, however, that the amplitude of anticipatory cortisol stress levels has a unique predictive value for psychological health. So far, no "best practice" in how to investigate the anticipatory cortisol stress response has emerged. The goal of the current research was to develop a protocol that would allow for a sensitive and easy-to-implement laboratory-based investigation into anticipatory cortisol stress levels. We initially tested 26 healthy men in either an anticipation- or stress-only condition of the Trier Social Stress Test (TSST) to map the distinct timelines of anticipatory and reactive cortisol release profiles (study 1). Subsequently, we administered the TSST to 50 healthy men such that the cortisol responses to anticipatory and reactive stress components could be dissociated (study 2). In both studies we sampled saliva cortisol at high frequency (at baseline, during 10min of anticipation and during and after 10min of acute stress) and the current mood state pre- and post-stress. We found anticipatory responder rates of 20% and 40%, with peak anticipatory cortisol levels between 14 and 20min after onset of anticipation. Visible changes in reactive cortisol levels occurred only after the termination of the acute stressor. We conclude that the best practice to detect a maximum number of anticipatory responders in the TSST would be to extend the anticipation phase to 15min. In doing so, the anticipatory cortisol peak could be captured at a time-point of the actual stressor that is uninfluenced by reactive cortisol levels. Overall, we could reveal several features of anticipatory responders. Most importantly, there was a positive correlation between anticipatory and reactive stress responses. There was no association between anticipatory cortisol and alpha-amylase as well as subjective-psychological stress responses. Future studies will have to determine whether the anticipatory responders differ with respect to various stress-sensitive parameters like sex, personality, psychological wellbeing or chronic stress.</dcterms:abstract>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <dc:contributor>Pruessner, Jens C.</dc:contributor>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-04-03T08:01:25Z</dcterms:available>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-04-03T08:01:25Z</dc:date>
    <dc:creator>Vogel, Susanne</dc:creator>
    <dc:language>eng</dc:language>
    <dc:creator>Duchesne, Annie</dc:creator>
    <dc:contributor>Engert, Veronika</dc:contributor>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/43"/>
    <dcterms:title>Differentiating anticipatory from reactive cortisol responses to psychosocial stress</dcterms:title>
    <dc:contributor>Efanov, Simona I.</dc:contributor>
    <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/38254"/>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/43"/>
    <dc:creator>Efanov, Simona I.</dc:creator>
    <dc:contributor>Corbo, Vincent</dc:contributor>
    <dc:creator>Engert, Veronika</dc:creator>
    <dc:creator>Pruessner, Jens C.</dc:creator>
    <dc:contributor>Duchesne, Annie</dc:contributor>
    <dcterms:issued>2013-08</dcterms:issued>
    <dc:contributor>Vogel, Susanne</dc:contributor>
    <dc:creator>Corbo, Vincent</dc:creator>
  </rdf:Description>
</rdf:RDF>
Internal note
xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter
Contact
URL of original publication
Test date of URL
Examination date of dissertation
Method of financing
Comment on publication
Alliance license
Corresponding Authors der Uni Konstanz vorhanden
International Co-Authors
Bibliography of Konstanz
No
Refereed