Comparison of a teratogenic transcriptome-based predictive test based on human embryonic versus inducible pluripotent stem cells

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2016
Autor:innen
Shinde, Vaibhav
Perumal Srinivasan, Sureshkumar
Henry, Margit
Rotshteyn, Tamara
Hescheler, Jürgen
Rahnenführer, Jörg
Grinberg, Marianna
Meisig, Johannes
Blüthgen, Nils
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Stem cell research & therapy. 2016, 7(1), 190. eISSN 1757-6512. Available under: doi: 10.1186/s13287-016-0449-2
Zusammenfassung

Human embryonic stem cells (hESCs) partially recapitulate early embryonic three germ layer development, allowing testing of potential teratogenic hazards. Because use of hESCs is ethically debated, we investigated the potential for human induced pluripotent stem cells (hiPSCs) to replace hESCs in such tests.

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570 Biowissenschaften, Biologie
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ISO 690SHINDE, Vaibhav, Sureshkumar PERUMAL SRINIVASAN, Margit HENRY, Tamara ROTSHTEYN, Jürgen HESCHELER, Jörg RAHNENFÜHRER, Marianna GRINBERG, Johannes MEISIG, Nils BLÜTHGEN, Tanja WALDMANN, Marcel LEIST, Jan Georg HENGSTLER, Agapios SACHINIDIS, 2016. Comparison of a teratogenic transcriptome-based predictive test based on human embryonic versus inducible pluripotent stem cells. In: Stem cell research & therapy. 2016, 7(1), 190. eISSN 1757-6512. Available under: doi: 10.1186/s13287-016-0449-2
BibTex
@article{Shinde2016Compa-36720,
  year={2016},
  doi={10.1186/s13287-016-0449-2},
  title={Comparison of a teratogenic transcriptome-based predictive test based on human embryonic versus inducible pluripotent stem cells},
  number={1},
  volume={7},
  journal={Stem cell research & therapy},
  author={Shinde, Vaibhav and Perumal Srinivasan, Sureshkumar and Henry, Margit and Rotshteyn, Tamara and Hescheler, Jürgen and Rahnenführer, Jörg and Grinberg, Marianna and Meisig, Johannes and Blüthgen, Nils and Waldmann, Tanja and Leist, Marcel and Hengstler, Jan Georg and Sachinidis, Agapios},
  note={Article Number: 190}
}
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