Recognition of Remote Mismatches by DNA Polymerases

Strerath, Michael; Gaster, Jens; Marx, Andreas

Recognition of Remote Mismatches by DNA Polymerases

Dateien

Zu diesem Dokument gibt es keine Dateien.

Datum

2004

Autor:innen

Strerath, Michael

Gaster, Jens

Marx, Andreas

DOI (zitierfähiger Link)

https://doi.org/10.1002/cbic.200400107

Sammlungen

Chemie

Publikationstyp

Zeitschriftenartikel

Publikationsstatus

Published

Erschienen in

ChemBioChem. 2004, 5(11), pp. 1585-1588. ISSN 1439-4227. eISSN 1439-7633. Available under: doi: 10.1002/cbic.200400107

Zusammenfassung

We show that DNA polymerases inspect mismatches within the primer–template complex up to four positions distal to the catalytic center, as shown. Insights into enzyme transitions were drawn by chemical probes and extended to direct analysis of single nucleotide variations through allele-specific PCR.

Fachgebiet (DDC)

540 Chemie

Zitieren

ISO 690

STRERATH, Michael, Jens GASTER, Andreas MARX, 2004. Recognition of Remote Mismatches by DNA Polymerases. In: ChemBioChem. 2004, 5(11), pp. 1585-1588. ISSN 1439-4227. eISSN 1439-7633. Available under: doi: 10.1002/cbic.200400107

BibTex

@article{Strerath2004-11-05Recog-33856,
  year={2004},
  doi={10.1002/cbic.200400107},
  title={Recognition of Remote Mismatches by DNA Polymerases},
  number={11},
  volume={5},
  issn={1439-4227},
  journal={ChemBioChem},
  pages={1585--1588},
  author={Strerath, Michael and Gaster, Jens and Marx, Andreas}
}

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