Recognition of Remote Mismatches by DNA Polymerases
Recognition of Remote Mismatches by DNA Polymerases
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2004
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ChemBioChem ; 5 (2004), 11. - pp. 1585-1588. - ISSN 1439-4227. - eISSN 1439-7633
Abstract
We show that DNA polymerases inspect mismatches within the primer–template complex up to four positions distal to the catalytic center, as shown. Insights into enzyme transitions were drawn by chemical probes and extended to direct analysis of single nucleotide variations through allele-specific PCR.
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540 Chemistry
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STRERATH, Michael, Jens GASTER, Andreas MARX, 2004. Recognition of Remote Mismatches by DNA Polymerases. In: ChemBioChem. 5(11), pp. 1585-1588. ISSN 1439-4227. eISSN 1439-7633. Available under: doi: 10.1002/cbic.200400107BibTex
@article{Strerath2004-11-05Recog-33856, year={2004}, doi={10.1002/cbic.200400107}, title={Recognition of Remote Mismatches by DNA Polymerases}, number={11}, volume={5}, issn={1439-4227}, journal={ChemBioChem}, pages={1585--1588}, author={Strerath, Michael and Gaster, Jens and Marx, Andreas} }
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