Publikation:

Statistical strategies and stochastic predictive models for the MARK-AGE data

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Giampieri_0-312547.pdf
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Datum

2015

Autor:innen

Giampieri, Enrico
Remondini, Daniel
Bacalini, Maria Giulia
Garagnani, Paolo
Pirazzini, Chiara
Yani, Stella Lukas
Giuliani, Cristina
Menichetti, Giulia
Zironi, Isabella
Sala, Claudia
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URI (zitierfähiger Link)
http://nbn-resolving.de/urn:nbn:de:bsz:352-0-312547
DOI (zitierfähiger Link)
https://doi.org/10.1016/j.mad.2015.07.001
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CC BY-NC-ND 4.0

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Open Access-Veröffentlichung
Open Access Hybrid

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Biologie: Publikationen
Core Facility der Universität Konstanz

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Titel in einer weiteren Sprache

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Published

Erschienen in

Mechanisms of Ageing and Development. 2015, 151, pp. 45-53. ISSN 0047-6374. eISSN 1872-6216. Available under: doi: 10.1016/j.mad.2015.07.001

Zusammenfassung

MARK-AGE aims at the identification of biomarkers of human aging capable of discriminating between the chronological age and the effective functional status of the organism. To achieve this, given the structure of the collected data, a proper statistical analysis has to be performed, as the structure of the data are non trivial and the number of features under study is near to the number of subjects used, requiring special care to avoid overfitting. Here we described some of the possible strategies suitable for this analysis. We also include a description of the main techniques used, to explain and justify the selected strategies. Among other possibilities, we suggest to model and analyze the data with a three step strategy.

Zusammenfassung in einer weiteren Sprache

Fachgebiet (DDC)
570 Biowissenschaften, Biologie

Schlagwörter

Biomarkers, Biological age, Chronological age, Statistics models, MARK-AGE

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ISO 690GIAMPIERI, Enrico, Daniel REMONDINI, Maria Giulia BACALINI, Paolo GARAGNANI, Chiara PIRAZZINI, Stella Lukas YANI, Cristina GIULIANI, Giulia MENICHETTI, Isabella ZIRONI, Claudia SALA, Miriam CAPRI, Claudio FRANCESCHI, Alexander BÜRKLE, Gastone CASTELLANI, 2015. Statistical strategies and stochastic predictive models for the MARK-AGE data. In: Mechanisms of Ageing and Development. 2015, 151, pp. 45-53. ISSN 0047-6374. eISSN 1872-6216. Available under: doi: 10.1016/j.mad.2015.07.001
BibTex
@article{Giampieri2015Stati-33339,
  year={2015},
  doi={10.1016/j.mad.2015.07.001},
  title={Statistical strategies and stochastic predictive models for the MARK-AGE data},
  volume={151},
  issn={0047-6374},
  journal={Mechanisms of Ageing and Development},
  pages={45--53},
  author={Giampieri, Enrico and Remondini, Daniel and Bacalini, Maria Giulia and Garagnani, Paolo and Pirazzini, Chiara and Yani, Stella Lukas and Giuliani, Cristina and Menichetti, Giulia and Zironi, Isabella and Sala, Claudia and Capri, Miriam and Franceschi, Claudio and Bürkle, Alexander and Castellani, Gastone}
}
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