Structure-Pattern-Based Total Synthesis
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2019
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European Union (EU): 679418
Projekt
ANaPSyS - Artifical Natural Products System Synthesis
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Core Facility der Universität Konstanz
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Published
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Chemistry - A European Journal. Wiley. 2019, 25(46), pp. 10782-10791. ISSN 0947-6539. eISSN 1521-3765. Available under: doi: 10.1002/chem.201901308
Zusammenfassung
In this article the concept of structure-pattern-recognition and its application to total synthesis is summarized. By applying this synthetic strategy to the two biogenetically unrelated natural product families Sarpagine and Stemona alkaloids, a drastic increase of synthetic efficiency could be achieved. To highlight its potential, this strategy is compared with some elegant target-oriented syntheses. The importance of strategic planning and synthesis design is clearly demonstrated.
Zusammenfassung in einer weiteren Sprache
Fachgebiet (DDC)
540 Chemie
Schlagwörter
alkaloids, biomimetic synthesis, cycloadditions, natural products, synthetic methods
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ISO 690
GERLINGER, Christa K. G., Tanja GAICH, 2019. Structure-Pattern-Based Total Synthesis. In: Chemistry - A European Journal. Wiley. 2019, 25(46), pp. 10782-10791. ISSN 0947-6539. eISSN 1521-3765. Available under: doi: 10.1002/chem.201901308BibTex
@article{Gerlinger2019-08-14Struc-46441, year={2019}, doi={10.1002/chem.201901308}, title={Structure-Pattern-Based Total Synthesis}, number={46}, volume={25}, issn={0947-6539}, journal={Chemistry - A European Journal}, pages={10782--10791}, author={Gerlinger, Christa K. G. and Gaich, Tanja} }
RDF
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