Structure-Pattern-Based Total Synthesis

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2019
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10.1002/chem.201901308
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oops
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679418
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ANaPSyS - Artifical Natural Products System Synthesis
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Chemistry - A European Journal ; 25 (2019), 46. - pp. 10782-10791. - Wiley. - ISSN 0947-6539. - eISSN 1521-3765
Abstract
In this article the concept of structure-pattern-recognition and its application to total synthesis is summarized. By applying this synthetic strategy to the two biogenetically unrelated natural product families Sarpagine and Stemona alkaloids, a drastic increase of synthetic efficiency could be achieved. To highlight its potential, this strategy is compared with some elegant target-oriented syntheses. The importance of strategic planning and synthesis design is clearly demonstrated.
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540 Chemistry
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alkaloids, biomimetic synthesis, cycloadditions, natural products, synthetic methods
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ISO 690GERLINGER, Christa K. G., Tanja GAICH, 2019. Structure-Pattern-Based Total Synthesis. In: Chemistry - A European Journal. Wiley. 25(46), pp. 10782-10791. ISSN 0947-6539. eISSN 1521-3765. Available under: doi: 10.1002/chem.201901308
BibTex
@article{Gerlinger2019-08-14Struc-46441,
  year={2019},
  doi={10.1002/chem.201901308},
  title={Structure-Pattern-Based Total Synthesis},
  number={46},
  volume={25},
  issn={0947-6539},
  journal={Chemistry - A European Journal},
  pages={10782--10791},
  author={Gerlinger, Christa K. G. and Gaich, Tanja}
}
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