Publikation:

Structure-Pattern-Based Total Synthesis

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2019

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https://doi.org/10.1002/chem.201901308
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European Union (EU): 679418

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ANaPSyS - Artifical Natural Products System Synthesis
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Chemie: Publikationen
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Published

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Chemistry - A European Journal. Wiley. 2019, 25(46), pp. 10782-10791. ISSN 0947-6539. eISSN 1521-3765. Available under: doi: 10.1002/chem.201901308

Zusammenfassung

In this article the concept of structure-pattern-recognition and its application to total synthesis is summarized. By applying this synthetic strategy to the two biogenetically unrelated natural product families Sarpagine and Stemona alkaloids, a drastic increase of synthetic efficiency could be achieved. To highlight its potential, this strategy is compared with some elegant target-oriented syntheses. The importance of strategic planning and synthesis design is clearly demonstrated.

Zusammenfassung in einer weiteren Sprache

Fachgebiet (DDC)
540 Chemie

Schlagwörter

alkaloids, biomimetic synthesis, cycloadditions, natural products, synthetic methods

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ISO 690GERLINGER, Christa K. G., Tanja GAICH, 2019. Structure-Pattern-Based Total Synthesis. In: Chemistry - A European Journal. Wiley. 2019, 25(46), pp. 10782-10791. ISSN 0947-6539. eISSN 1521-3765. Available under: doi: 10.1002/chem.201901308
BibTex
@article{Gerlinger2019-08-14Struc-46441,
  year={2019},
  doi={10.1002/chem.201901308},
  title={Structure-Pattern-Based Total Synthesis},
  number={46},
  volume={25},
  issn={0947-6539},
  journal={Chemistry - A European Journal},
  pages={10782--10791},
  author={Gerlinger, Christa K. G. and Gaich, Tanja}
}
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