DNA polymerase-catalyzed incorporation of nucleotides modified with a G-quadruplex-derived DNAzyme
DNA polymerase-catalyzed incorporation of nucleotides modified with a G-quadruplex-derived DNAzyme
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2015
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Chemical Communications ; 51 (2015), 34. - pp. 7379-7381. - ISSN 0009-241X. - eISSN 1364-548X
Abstract
We show that nucleotides which are modified with a G-quadruplex-derived DNAzyme are substrates for DNA polymerases. Based on this finding we developed a naked-eye detection system that allows the detection of single nucleotide variations in DNA.
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540 Chemistry
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VERGA, Daniela, Moritz WELTER, Anna-Lena STECK, Andreas MARX, 2015. DNA polymerase-catalyzed incorporation of nucleotides modified with a G-quadruplex-derived DNAzyme. In: Chemical Communications. 51(34), pp. 7379-7381. ISSN 0009-241X. eISSN 1364-548X. Available under: doi: 10.1039/C5CC01387ABibTex
@article{Verga2015polym-30983, year={2015}, doi={10.1039/C5CC01387A}, title={DNA polymerase-catalyzed incorporation of nucleotides modified with a G-quadruplex-derived DNAzyme}, number={34}, volume={51}, issn={0009-241X}, journal={Chemical Communications}, pages={7379--7381}, author={Verga, Daniela and Welter, Moritz and Steck, Anna-Lena and Marx, Andreas} }
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