The function of intersegmental connections in determining temporal characteristics of the spinal cord rhythmic output

No Thumbnail Available
Files
There are no files associated with this item.
Date
2007
Authors
Ben-Jacob, Eshel
Cohen, Avis
Editors
Contact
Journal ISSN
Electronic ISSN
ISBN
Bibliographical data
Publisher
Series
URI (citable link)
ArXiv-ID
International patent number
Link to the license
oops
EU project number
Project
Open Access publication
Collections
Restricted until
Title in another language
Research Projects
Organizational Units
Journal Issue
Publication type
Journal article
Publication status
Published
Published in
Neuroscience ; 147 (2007), 1. - pp. 236-246. - ISSN 0306-4522. - eISSN 1873-7544
Abstract
Recent renewed interest in the study of rhythmic behaviors and pattern-generating circuits has been inspired by the currently well-established role of oscillating neuronal networks in all aspects of the function of our nervous system: from sensory integration to central processing, and of course motor control. An integrative rather than reductionist approach in the study of pattern-generating circuits is in accordance with current developments. The lamprey spinal cord, a relatively simple and much-studied preparation, is a useful model for such a study. It is an example of a chain of coupled oscillatory units that is characterized by its ability to demonstrate robust coordinated rhythmic output when isolated in vitro. The preparation allows maximum control over the chemical (neuromodulators and hormones) as well as neuronal environment (sensory and descending inputs) of the single oscillatory unit: the pattern-generating circuit. The current study made use of recently developed tools for nonlinear analysis of time-series, specifically neurophysiological signals. These tools allow us to reveal and characterize biological-functional complexity and information capacity of the neuronal output recorded from the lamprey model network. We focused on the importance of different types of inputs to an oscillatory network and their effect on the network's functional output. We show that the basic circuit, when isolated from short- and long-range neuronal inputs, demonstrates its full potential of information capacity: maximal variation quantities and elevated functional complexity. Morphological and functional constraints result in the network exhibiting only a limited range of the above. This constitutes an important substrate for plasticity in neuronal network function.
Summary in another language
Subject (DDC)
570 Biosciences, Biology
Keywords
central pattern generator, lamprey, cross-correlation, complexity
Conference
Review
undefined / . - undefined, undefined. - (undefined; undefined)
Cite This
ISO 690AYALI, Amir, Einat COUZIN-FUCHS, Eshel BEN-JACOB, Avis COHEN, 2007. The function of intersegmental connections in determining temporal characteristics of the spinal cord rhythmic output. In: Neuroscience. 147(1), pp. 236-246. ISSN 0306-4522. eISSN 1873-7544. Available under: doi: 10.1016/j.neuroscience.2007.04.014
BibTex
@article{Ayali2007-06-15funct-46904,
  year={2007},
  doi={10.1016/j.neuroscience.2007.04.014},
  title={The function of intersegmental connections in determining temporal characteristics of the spinal cord rhythmic output},
  number={1},
  volume={147},
  issn={0306-4522},
  journal={Neuroscience},
  pages={236--246},
  author={Ayali, Amir and Couzin-Fuchs, Einat and Ben-Jacob, Eshel and Cohen, Avis}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/46904">
    <dcterms:issued>2007-06-15</dcterms:issued>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2019-09-17T12:40:41Z</dcterms:available>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dc:contributor>Cohen, Avis</dc:contributor>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dc:contributor>Couzin-Fuchs, Einat</dc:contributor>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dc:creator>Couzin-Fuchs, Einat</dc:creator>
    <dc:contributor>Ben-Jacob, Eshel</dc:contributor>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/46904"/>
    <dc:contributor>Ayali, Amir</dc:contributor>
    <dc:creator>Ben-Jacob, Eshel</dc:creator>
    <dcterms:abstract xml:lang="eng">Recent renewed interest in the study of rhythmic behaviors and pattern-generating circuits has been inspired by the currently well-established role of oscillating neuronal networks in all aspects of the function of our nervous system: from sensory integration to central processing, and of course motor control. An integrative rather than reductionist approach in the study of pattern-generating circuits is in accordance with current developments. The lamprey spinal cord, a relatively simple and much-studied preparation, is a useful model for such a study. It is an example of a chain of coupled oscillatory units that is characterized by its ability to demonstrate robust coordinated rhythmic output when isolated in vitro. The preparation allows maximum control over the chemical (neuromodulators and hormones) as well as neuronal environment (sensory and descending inputs) of the single oscillatory unit: the pattern-generating circuit. The current study made use of recently developed tools for nonlinear analysis of time-series, specifically neurophysiological signals. These tools allow us to reveal and characterize biological-functional complexity and information capacity of the neuronal output recorded from the lamprey model network. We focused on the importance of different types of inputs to an oscillatory network and their effect on the network's functional output. We show that the basic circuit, when isolated from short- and long-range neuronal inputs, demonstrates its full potential of information capacity: maximal variation quantities and elevated functional complexity. Morphological and functional constraints result in the network exhibiting only a limited range of the above. This constitutes an important substrate for plasticity in neuronal network function.</dcterms:abstract>
    <dc:creator>Cohen, Avis</dc:creator>
    <dc:language>eng</dc:language>
    <dcterms:title>The function of intersegmental connections in determining temporal characteristics of the spinal cord rhythmic output</dcterms:title>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2019-09-17T12:40:41Z</dc:date>
    <dc:creator>Ayali, Amir</dc:creator>
  </rdf:Description>
</rdf:RDF>
Internal note
xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter
Contact
URL of original publication
Test date of URL
Examination date of dissertation
Method of financing
Comment on publication
Alliance license
Corresponding Authors der Uni Konstanz vorhanden
International Co-Authors
Bibliography of Konstanz
No
Refereed
Yes