@article{Terzaki2013-12Miner-43503,
  year={2013},
  doi={10.1088/1758-5082/5/4/045002},
  title={Mineralized self-assembled peptides on 3D laser-made scaffolds : a new route toward 'scaffold on scaffold' hard tissue engineering},
  number={4},
  volume={5},
  issn={1758-5082},
  journal={Biofabrication},
  author={Terzaki, Konstantina and Kalloudi, Erifyli and Mossou, Estelle and Mitchell, Edward P. and Forsyth, V. Trevor and Sturm, Elena V. and Simon, Paul and Vamvakaki, Maria and Chatzinikolaidou, Maria and Mitraki, Anna and Farsari, Maria},
  note={Article Number: 045002}
}

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    <dc:contributor>Mitraki, Anna</dc:contributor>
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    <dc:creator>Kalloudi, Erifyli</dc:creator>
    <dc:contributor>Mossou, Estelle</dc:contributor>
    <dcterms:title>Mineralized self-assembled peptides on 3D laser-made scaffolds : a new route toward 'scaffold on scaffold' hard tissue engineering</dcterms:title>
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    <dcterms:abstract xml:lang="eng">In this study, we propose a new approach to hard tissue regeneration based on the mineralization of 3D scaffolds made using lasers. To this end, we report the rational design of aspartate-containing self-assembling peptides targeted for calcium binding. We further investigate the suitability of these peptides to support cell attachment and proliferation when coupled on a hybrid organic–inorganic structurable material, and evaluate the response of pre-osteoblastic cells on functionalized 3D scaffolds and material surfaces. Our results show that the mineralized peptide, when immobilized on a hybrid photo-structurable material strongly supports cell adhesion, a proliferation increase after three and seven days in culture, and exhibits a statistically significant increase of biomineralization. We propose this strategy as a 'scaffold on scaffold' approach for hard tissue regeneration.</dcterms:abstract>
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    <dc:contributor>Chatzinikolaidou, Maria</dc:contributor>
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    <dc:contributor>Terzaki, Konstantina</dc:contributor>
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