Bubbles, clusters and denaturation in genomic DNA : modeling, parametrization, efficient computation

dc.contributor.authorTheodorakopoulos, Nikos
dc.date.accessioned2020-09-29T09:08:52Z
dc.date.available2020-09-29T09:08:52Z
dc.date.issued2011eng
dc.description.abstractThe paper uses mesoscopic, nonlinear lattice dynamics based (Peyrard–Bishop–Dauxois, PBD) modeling to describe thermal properties of DNA below and near the denaturation temperature. Computationally efficient notation is introduced for the relevant statistical mechanics. Computed melting profiles of long and short heterogeneous sequences are presented, using a recently introduced reparametrization of the PBD model, and critically discussed. The statistics of extended open bubbles and bound clusters is formulated and results are presented for selected examples.eng
dc.description.versionpublishedde
dc.identifier.arxiv1102.0259eng
dc.identifier.doi10.1142/S1402925111001611eng
dc.identifier.urihttps://kops.uni-konstanz.de/handle/123456789/51085
dc.language.isoengeng
dc.subjectDNA melting, denaturation bubbles, Peyrard–Bishop–Dauxois (PBD) modeleng
dc.subject.ddc530eng
dc.titleBubbles, clusters and denaturation in genomic DNA : modeling, parametrization, efficient computationeng
dc.typeJOURNAL_ARTICLEde
dspace.entity.typePublication
kops.citation.bibtex
@article{Theodorakopoulos2011Bubbl-51085,
  year={2011},
  doi={10.1142/S1402925111001611},
  title={Bubbles, clusters and denaturation in genomic DNA : modeling, parametrization, efficient computation},
  number={Suppl. 2},
  volume={18},
  issn={1402-9251},
  journal={Journal of Nonlinear Mathematical Physics},
  pages={429--447},
  author={Theodorakopoulos, Nikos}
}
kops.citation.iso690THEODORAKOPOULOS, Nikos, 2011. Bubbles, clusters and denaturation in genomic DNA : modeling, parametrization, efficient computation. In: Journal of Nonlinear Mathematical Physics. Taylor & Francis. 2011, 18(Suppl. 2), pp. 429-447. ISSN 1402-9251. eISSN 1776-0852. Available under: doi: 10.1142/S1402925111001611deu
kops.citation.iso690THEODORAKOPOULOS, Nikos, 2011. Bubbles, clusters and denaturation in genomic DNA : modeling, parametrization, efficient computation. In: Journal of Nonlinear Mathematical Physics. Taylor & Francis. 2011, 18(Suppl. 2), pp. 429-447. ISSN 1402-9251. eISSN 1776-0852. Available under: doi: 10.1142/S1402925111001611eng
kops.citation.rdf
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/51085">
    <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/51085"/>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2020-09-29T09:08:52Z</dcterms:available>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <dcterms:issued>2011</dcterms:issued>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2020-09-29T09:08:52Z</dc:date>
    <dcterms:title>Bubbles, clusters and denaturation in genomic DNA : modeling, parametrization, efficient computation</dcterms:title>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/41"/>
    <dc:language>eng</dc:language>
    <dcterms:abstract xml:lang="eng">The paper uses mesoscopic, nonlinear lattice dynamics based (Peyrard–Bishop–Dauxois, PBD) modeling to describe thermal properties of DNA below and near the denaturation temperature. Computationally efficient notation is introduced for the relevant statistical mechanics. Computed melting profiles of long and short heterogeneous sequences are presented, using a recently introduced reparametrization of the PBD model, and critically discussed. The statistics of extended open bubbles and bound clusters is formulated and results are presented for selected examples.</dcterms:abstract>
    <dc:creator>Theodorakopoulos, Nikos</dc:creator>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/41"/>
    <dc:contributor>Theodorakopoulos, Nikos</dc:contributor>
  </rdf:Description>
</rdf:RDF>
kops.flag.isPeerReviewedunknowneng
kops.flag.knbibliographytrue
kops.sourcefieldJournal of Nonlinear Mathematical Physics. Taylor & Francis. 2011, <b>18</b>(Suppl. 2), pp. 429-447. ISSN 1402-9251. eISSN 1776-0852. Available under: doi: 10.1142/S1402925111001611deu
kops.sourcefield.plainJournal of Nonlinear Mathematical Physics. Taylor & Francis. 2011, 18(Suppl. 2), pp. 429-447. ISSN 1402-9251. eISSN 1776-0852. Available under: doi: 10.1142/S1402925111001611deu
kops.sourcefield.plainJournal of Nonlinear Mathematical Physics. Taylor & Francis. 2011, 18(Suppl. 2), pp. 429-447. ISSN 1402-9251. eISSN 1776-0852. Available under: doi: 10.1142/S1402925111001611eng
relation.isAuthorOfPublication6d489fee-21a4-4ce8-8d24-845ee1db9326
relation.isAuthorOfPublication.latestForDiscovery6d489fee-21a4-4ce8-8d24-845ee1db9326
source.bibliographicInfo.fromPage429eng
source.bibliographicInfo.issueSuppl. 2eng
source.bibliographicInfo.toPage447eng
source.bibliographicInfo.volume18eng
source.identifier.eissn1776-0852eng
source.identifier.issn1402-9251eng
source.periodicalTitleJournal of Nonlinear Mathematical Physicseng
source.publisherTaylor & Franciseng

Dateien