Nucleotides : Part LXXIX ; New building blocks for photolithographic syntheses of oligoribonucleotides

Hermann, Christoph; Kvassiouk, Evgeny; Pfleiderer, Wolfgang

Nucleotides : Part LXXIX ; New building blocks for photolithographic syntheses of oligoribonucleotides

Dateien

Zu diesem Dokument gibt es keine Dateien.

Datum

2011

Autor:innen

Hermann, Christoph

Kvassiouk, Evgeny

Pfleiderer, Wolfgang

Publikationstyp

Zeitschriftenartikel

Publikationsstatus

Published

Erschienen in

Helvetica Chimica Acta. 2011, 94(3), pp. 362-370. ISSN 0018-019X. Available under: doi: 10.1002/hlca.201000403

Zusammenfassung

Two series of new ribonucleoside 3′-phosphoramidites (see 36–42) carrying the photolabile [2-(2-nitrophenyl)propoxy]carbonyl group at the 5′-O-position were synthesized and characterized as monomeric building blocks for photolithographic syntheses of RNA chips. Base protection was achieved in the well-known manner by the 2-(4-nitrophenyl)ethyl (npe) and the [2-(4-nitrophenyl)ethoxy]carbonyl (npeoc) group. The carbohydrate moiety carried in addition the 2′-O-(tetrahydro-4-methoxy-2H-pyran-4-yl) group for blocking the 2′-OH function.

Fachgebiet (DDC)

540 Chemie

Schlagwörter

ribonucleoside 3′-phosphoramidites, photolithographic synthesis, oligoribonucleotides, nucleotides

Zitieren

ISO 690

HERMANN, Christoph, Evgeny KVASSIOUK, Wolfgang PFLEIDERER, 2011. Nucleotides : Part LXXIX ; New building blocks for photolithographic syntheses of oligoribonucleotides. In: Helvetica Chimica Acta. 2011, 94(3), pp. 362-370. ISSN 0018-019X. Available under: doi: 10.1002/hlca.201000403

BibTex

@article{Hermann2011Nucle-19905,
  year={2011},
  doi={10.1002/hlca.201000403},
  title={Nucleotides : Part LXXIX ; New building blocks for photolithographic syntheses of oligoribonucleotides},
  number={3},
  volume={94},
  issn={0018-019X},
  journal={Helvetica Chimica Acta},
  pages={362--370},
  author={Hermann, Christoph and Kvassiouk, Evgeny and Pfleiderer, Wolfgang}
}

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