Food for thought on the evolution of toxicology and the phasing out of animal testing

Loading...
Thumbnail Image
Date
2008
Editors
Contact
Journal ISSN
Electronic ISSN
ISBN
Bibliographical data
Publisher
Series
DOI (citable link)
ArXiv-ID
International patent number
Link to the license
EU project number
Project
Open Access publication
Collections
Restricted until
Title in another language
Research Projects
Organizational Units
Journal Issue
Publication type
Journal article
Publication status
Published in
Altex ; 25 (2008), 2. - pp. 91-96
Abstract
There is something brewing in the field of toxicology: Last year's vision and strategy document published by the US National Academy of Sciences (NRC, 2007) has excited many toxicologists on both sides of the Atlantic. In February 2008 several American agencies announced a coalition to set this into practice (www.sciencemag.org/content/vol319/issue 5865/index.dtl): We propose a shift from primarily in vivo animal studies to in vitro assays, in vivo assays with lower organisms, and computational modeling for toxicity assessments . In USA Today of the same day we find a comment by Francis Collin, Director of the National Human Genome Research Institute: [Toxicity testing] was expensive, time-consuming, used animals in large numbers and didn t always work . In the same article, Elias Zerhouni, Director of the NIH, is cited: Animal testing won t disappear overnight, but the agencies work signals the beginning of an end. We have never heard anything like that from US federal agency representatives before. What is going on? What can we really expect and when?
Summary in another language
Subject (DDC)
570 Biosciences, Biology
Keywords
Conference
Review
undefined / . - undefined, undefined. - (undefined; undefined)
Cite This
ISO 690HARTUNG, Thomas, Marcel LEIST, 2008. Food for thought on the evolution of toxicology and the phasing out of animal testing. In: Altex. 25(2), pp. 91-96
BibTex
@article{Hartung2008thoug-8336,
  year={2008},
  title={Food for thought   on the evolution of toxicology and the phasing out of animal testing},
  number={2},
  volume={25},
  journal={Altex},
  pages={91--96},
  author={Hartung, Thomas and Leist, Marcel}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/8336">
    <dcterms:abstract xml:lang="eng">There is something brewing in the field of toxicology: Last year's vision and strategy document published by the US National Academy of Sciences (NRC, 2007) has excited many toxicologists on both sides of the Atlantic. In February 2008 several American agencies announced a coalition to set this into practice (www.sciencemag.org/content/vol319/issue 5865/index.dtl):  We propose a shift from primarily in vivo animal studies to in vitro assays, in vivo assays with lower organisms, and computational modeling for toxicity assessments . In USA Today of the same day we find a comment by Francis Collin, Director of the National Human Genome Research Institute:  [Toxicity testing] was expensive, time-consuming, used animals in large numbers and didn t always work . In the same article, Elias Zerhouni, Director of the NIH, is cited:  Animal testing won t disappear overnight, but the agencies  work signals the beginning of an end.  We have never heard anything like that from US federal agency representatives before. What is going on? What can we really expect and when?</dcterms:abstract>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dcterms:bibliographicCitation>First publ. in: Altex 25 (2008), 2, pp. 91-96</dcterms:bibliographicCitation>
    <dc:format>application/pdf</dc:format>
    <dc:rights>terms-of-use</dc:rights>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <dcterms:rights rdf:resource="https://rightsstatements.org/page/InC/1.0/"/>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dc:creator>Leist, Marcel</dc:creator>
    <dcterms:title>Food for thought   on the evolution of toxicology and the phasing out of animal testing</dcterms:title>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-24T17:42:46Z</dcterms:available>
    <dc:contributor>Leist, Marcel</dc:contributor>
    <dc:creator>Hartung, Thomas</dc:creator>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-24T17:42:46Z</dc:date>
    <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/8336/1/Altex2008hartungLeistUK.pdf"/>
    <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/8336/1/Altex2008hartungLeistUK.pdf"/>
    <dcterms:issued>2008</dcterms:issued>
    <dc:contributor>Hartung, Thomas</dc:contributor>
    <dc:language>eng</dc:language>
    <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/8336"/>
  </rdf:Description>
</rdf:RDF>
Internal note
xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter
Contact
URL of original publication
Test date of URL
Examination date of dissertation
Method of financing
Comment on publication
Alliance license
Corresponding Authors der Uni Konstanz vorhanden
International Co-Authors
Bibliography of Konstanz
Yes
Refereed