Publikation:

Dissection of the cAMP induced cytosolic calcium response in Dictyostelium discoideum : the role of cAMP receptor subtypes and G protein subunits

Lade...
Vorschaubild

Dateien

Zu diesem Dokument gibt es keine Dateien.

Datum

1998

Autor:innen

Herausgeber:innen

Kontakt

ISSN der Zeitschrift

Electronic ISSN

ISBN

Bibliografische Daten

Verlag

Schriftenreihe

Auflagebezeichnung

URI (zitierfähiger Link)
ArXiv-ID

Internationale Patentnummer

Angaben zur Forschungsförderung

Projekt

Open Access-Veröffentlichung
Core Facility der Universität Konstanz

Gesperrt bis

Titel in einer weiteren Sprache

Publikationstyp
Zeitschriftenartikel
Publikationsstatus
Published

Erschienen in

FEBS Letters. Wiley. 1998, 436(2), pp. 271-276. ISSN 0014-5793. eISSN 1873-3468. Available under: doi: 10.1016/S0014-5793(98)01139-9

Zusammenfassung

The cAMP signaling cascade leading to changes in [Ca2+]i in Dictyostelium discoideum was analyzed using cell lines overexpressing single cAMP receptor subtypes (cAR1–cAR3) or lacking the Gα2 or Gβ subunit of the G protein. Imaging of fura2‐dextran‐loaded amoebae revealed cAMP‐induced [Ca2+]i changes characteristic for each receptor subtype activated. Cells expressing distinct subtypes sort to defined zones during multicellular development suggesting involvement of the specific [Ca2+]i transients in patterning processes. Whereas generation of the [Ca2+]i increase was Gα2‐independent, only few cells devoid of Gβ displayed a [Ca2+]i change after stimulation indicating its participation in the regulation of the calcium homeostasis.

Zusammenfassung in einer weiteren Sprache

Fachgebiet (DDC)
570 Biowissenschaften, Biologie

Schlagwörter

Konferenz

Rezension
undefined / . - undefined, undefined

Forschungsvorhaben

Organisationseinheiten

Zeitschriftenheft

Zugehörige Datensätze in KOPS

Zitieren

ISO 690SONNEMANN, Jürgen, Annette AICHEM, Christina SCHLATTERER, 1998. Dissection of the cAMP induced cytosolic calcium response in Dictyostelium discoideum : the role of cAMP receptor subtypes and G protein subunits. In: FEBS Letters. Wiley. 1998, 436(2), pp. 271-276. ISSN 0014-5793. eISSN 1873-3468. Available under: doi: 10.1016/S0014-5793(98)01139-9
BibTex
@article{Sonnemann1998-10-15Disse-49755,
  year={1998},
  doi={10.1016/S0014-5793(98)01139-9},
  title={Dissection of the cAMP induced cytosolic calcium response in Dictyostelium discoideum : the role of cAMP receptor subtypes and G protein subunits},
  number={2},
  volume={436},
  issn={0014-5793},
  journal={FEBS Letters},
  pages={271--276},
  author={Sonnemann, Jürgen and Aichem, Annette and Schlatterer, Christina}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/49755">
    <dcterms:abstract xml:lang="eng">The cAMP signaling cascade leading to changes in [Ca&lt;sup&gt;2+&lt;/sup&gt;]&lt;sub&gt;i&lt;/sub&gt; in Dictyostelium discoideum was analyzed using cell lines overexpressing single cAMP receptor subtypes (cAR1–cAR3) or lacking the G&lt;sub&gt;α2&lt;/sub&gt; or G&lt;sub&gt;β&lt;/sub&gt; subunit of the G protein. Imaging of fura2‐dextran‐loaded amoebae revealed cAMP‐induced [Ca&lt;sup&gt;2+&lt;/sup&gt;]&lt;sub&gt;i&lt;/sub&gt; changes characteristic for each receptor subtype activated. Cells expressing distinct subtypes sort to defined zones during multicellular development suggesting involvement of the specific [Ca&lt;sup&gt;2+&lt;/sup&gt;]&lt;sub&gt;i&lt;/sub&gt; transients in patterning processes. Whereas generation of the [Ca&lt;sup&gt;2+&lt;/sup&gt;]&lt;sub&gt;i&lt;/sub&gt; increase was G&lt;sub&gt;α2&lt;/sub&gt;‐independent, only few cells devoid of G&lt;sub&gt;β&lt;/sub&gt; displayed a [Ca&lt;sup&gt;2+&lt;/sup&gt;]&lt;sub&gt;i&lt;/sub&gt; change after stimulation indicating its participation in the regulation of the calcium homeostasis.</dcterms:abstract>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <dcterms:rights rdf:resource="https://rightsstatements.org/page/InC/1.0/"/>
    <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/49755"/>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dc:language>eng</dc:language>
    <dcterms:title>Dissection of the cAMP induced cytosolic calcium response in Dictyostelium discoideum : the role of cAMP receptor subtypes and G protein subunits</dcterms:title>
    <dc:contributor>Sonnemann, Jürgen</dc:contributor>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2020-05-29T09:47:05Z</dcterms:available>
    <dc:contributor>Schlatterer, Christina</dc:contributor>
    <dc:contributor>Aichem, Annette</dc:contributor>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2020-05-29T09:47:05Z</dc:date>
    <dc:rights>terms-of-use</dc:rights>
    <dc:creator>Sonnemann, Jürgen</dc:creator>
    <dc:creator>Schlatterer, Christina</dc:creator>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dc:creator>Aichem, Annette</dc:creator>
    <dcterms:issued>1998-10-15</dcterms:issued>
  </rdf:Description>
</rdf:RDF>

Interner Vermerk

xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter

Kontakt
URL der Originalveröffentl.

Prüfdatum der URL

Prüfungsdatum der Dissertation

Finanzierungsart

Kommentar zur Publikation

Allianzlizenz
Corresponding Authors der Uni Konstanz vorhanden
Internationale Co-Autor:innen
Universitätsbibliographie
Nein
Begutachtet
Ja
Diese Publikation teilen