Novel bacterial molybdenum and tungsten enzymes : three-dimensional structure, spectroscopy, and reaction mechanism

Lade...
Vorschaubild
Dateien
Boll_Schink_2005.pdf
Boll_Schink_2005.pdfGröße: 211.65 KBDownloads: 403
Datum
2005
Autor:innen
Boll, Matthias
Messerschmidt, A.
Herausgeber:innen
Kontakt
ISSN der Zeitschrift
Electronic ISSN
ISBN
Bibliografische Daten
Verlag
Schriftenreihe
Auflagebezeichnung
DOI (zitierfähiger Link)
ArXiv-ID
Internationale Patentnummer
Angaben zur Forschungsförderung
Projekt
Open Access-Veröffentlichung
Open Access Green
Core Facility der Universität Konstanz
Gesperrt bis
Titel in einer weiteren Sprache
Forschungsvorhaben
Organisationseinheiten
Zeitschriftenheft
Publikationstyp
Zeitschriftenartikel
Publikationsstatus
Published
Erschienen in
Zusammenfassung

The molybdenum enzymes 4-hydroxybenzoyl-CoA reductase and pyrogallol-phloroglucinol transhydroxylase and the tungsten enzyme acetylene hydratase catalyze reductive dehydroxylation reactions, i.e., transhydroxylation between phenolic residues and the addition of water to a triple bond. Such activities are unusual for this class of enzymes, which carry either a mononuclear Mo or W center. Crystallization and subsequent structural analysis by high-resolution X-ray crystallography has helped to resolve the reaction centers of these enzymes to a degree that allows us to understand the interaction of the enzyme and the respective substrate(s) in detail, and to develop a concept for the respective reaction mechanism, at least in two cases.

Zusammenfassung in einer weiteren Sprache
Fachgebiet (DDC)
570 Biowissenschaften, Biologie
Schlagwörter
Konferenz
Rezension
undefined / . - undefined, undefined
Zitieren
ISO 690BOLL, Matthias, Bernhard SCHINK, A. MESSERSCHMIDT, Peter M. H. KRONECK, 2005. Novel bacterial molybdenum and tungsten enzymes : three-dimensional structure, spectroscopy, and reaction mechanism. In: Biological Chemistry. 2005, 386(10), pp. 999-2006
BibTex
@article{Boll2005Novel-7162,
  year={2005},
  title={Novel bacterial molybdenum and tungsten enzymes : three-dimensional structure, spectroscopy, and reaction mechanism},
  number={10},
  volume={386},
  journal={Biological Chemistry},
  pages={999--2006},
  author={Boll, Matthias and Schink, Bernhard and Messerschmidt, A. and Kroneck, Peter M. H.}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/7162">
    <dcterms:rights rdf:resource="https://rightsstatements.org/page/InC/1.0/"/>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dc:creator>Messerschmidt, A.</dc:creator>
    <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/7162/1/Boll_Schink_2005.pdf"/>
    <dc:contributor>Messerschmidt, A.</dc:contributor>
    <dc:creator>Schink, Bernhard</dc:creator>
    <dcterms:bibliographicCitation>First publ. in: Biological Chemistry 386 (2005), 10, pp. 999-2006</dcterms:bibliographicCitation>
    <dc:contributor>Kroneck, Peter M. H.</dc:contributor>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-24T17:32:20Z</dcterms:available>
    <dc:format>application/pdf</dc:format>
    <dc:language>eng</dc:language>
    <dcterms:issued>2005</dcterms:issued>
    <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/7162"/>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-24T17:32:20Z</dc:date>
    <dc:creator>Kroneck, Peter M. H.</dc:creator>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/7162/1/Boll_Schink_2005.pdf"/>
    <dcterms:abstract xml:lang="deu">The molybdenum enzymes 4-hydroxybenzoyl-CoA reductase and pyrogallol-phloroglucinol transhydroxylase and the tungsten enzyme acetylene hydratase catalyze reductive dehydroxylation reactions, i.e., transhydroxylation between phenolic residues and the addition of water to a triple bond. Such activities are unusual for this class of enzymes, which carry either a mononuclear Mo or W center. Crystallization and subsequent structural analysis by high-resolution X-ray crystallography has helped to resolve the reaction centers of these enzymes to a degree that allows us to understand the interaction of the enzyme and the respective substrate(s) in detail, and to develop a concept for the respective reaction mechanism, at least in two cases.</dcterms:abstract>
    <dcterms:title>Novel bacterial molybdenum and tungsten enzymes : three-dimensional structure, spectroscopy, and reaction mechanism</dcterms:title>
    <dc:contributor>Schink, Bernhard</dc:contributor>
    <dc:rights>terms-of-use</dc:rights>
    <dc:contributor>Boll, Matthias</dc:contributor>
    <dc:creator>Boll, Matthias</dc:creator>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
  </rdf:Description>
</rdf:RDF>
Interner Vermerk
xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter
Kontakt
URL der Originalveröffentl.
Prüfdatum der URL
Prüfungsdatum der Dissertation
Finanzierungsart
Kommentar zur Publikation
Allianzlizenz
Corresponding Authors der Uni Konstanz vorhanden
Internationale Co-Autor:innen
Universitätsbibliographie
Ja
Begutachtet
Diese Publikation teilen