Novel bacterial molybdenum and tungsten enzymes : three-dimensional structure, spectroscopy, and reaction mechanism

Boll, Matthias; Schink, Bernhard; Messerschmidt, A.; Kroneck, Peter M. H.

Novel bacterial molybdenum and tungsten enzymes : three-dimensional structure, spectroscopy, and reaction mechanism

Dateien

Boll_Schink_2005.pdfGröße: 211.65 KBDownloads: 418

Datum

2005

Autor:innen

Boll, Matthias

Schink, Bernhard

Messerschmidt, A.

Kroneck, Peter M. H.

URI (zitierfähiger Link)

http://nbn-resolving.de/urn:nbn:de:bsz:352-opus-23321

Link zur Lizenz

Urheberrechtlich geschützt

Open Access-Veröffentlichung

Open Access Green

Sammlungen

Biologie

Publikationstyp

Zeitschriftenartikel

Publikationsstatus

Published

Erschienen in

Biological Chemistry. 2005, 386(10), pp. 999-2006

Zusammenfassung

The molybdenum enzymes 4-hydroxybenzoyl-CoA reductase and pyrogallol-phloroglucinol transhydroxylase and the tungsten enzyme acetylene hydratase catalyze reductive dehydroxylation reactions, i.e., transhydroxylation between phenolic residues and the addition of water to a triple bond. Such activities are unusual for this class of enzymes, which carry either a mononuclear Mo or W center. Crystallization and subsequent structural analysis by high-resolution X-ray crystallography has helped to resolve the reaction centers of these enzymes to a degree that allows us to understand the interaction of the enzyme and the respective substrate(s) in detail, and to develop a concept for the respective reaction mechanism, at least in two cases.

Fachgebiet (DDC)

570 Biowissenschaften, Biologie

Zitieren

ISO 690

BOLL, Matthias, Bernhard SCHINK, A. MESSERSCHMIDT, Peter M. H. KRONECK, 2005. Novel bacterial molybdenum and tungsten enzymes : three-dimensional structure, spectroscopy, and reaction mechanism. In: Biological Chemistry. 2005, 386(10), pp. 999-2006

BibTex

@article{Boll2005Novel-7162,
  year={2005},
  title={Novel bacterial molybdenum and tungsten enzymes : three-dimensional structure, spectroscopy, and reaction mechanism},
  number={10},
  volume={386},
  journal={Biological Chemistry},
  pages={999--2006},
  author={Boll, Matthias and Schink, Bernhard and Messerschmidt, A. and Kroneck, Peter M. H.}
}

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Universitätsbibliographie

Ja