Evaporative phase separation in polymer microdroplets with confinement and internal flow

Kurzanzeige
dc.contributor.authorKumar, Mukesh
dc.contributor.authorGopu, Maheshwar Reddy
dc.contributor.authorPugalneelam Parameswaran, Senthan
dc.contributor.authorJoshi, Prerak
dc.contributor.authorMampallil, Dileep
dc.date.accessioned2025-01-08T09:23:45Z
dc.date.available2025-01-08T09:23:45Z
dc.date.issued2024-04
dc.description.abstractEvaporation can drive initially homogeneous multiphase liquid systems out of equilibrium to induce liquid-liquid phase separation (LLPS). Here, we demonstrate evaporative LLPS in microfluidic-generated emulsion microdroplets of polymer mixtures. The evaporation produces distinct polymer phases within the microdroplets. Phase separation occurs even with polymer combinations that do not form distinct phases in sessile droplet evaporation. We attribute this aspect to evaporation-driven solutal Marangoni flows and the interface capture accumulating the nuclei at the apex where the evaporation rate is the maximum. A fast coalescence and growth of the accumulated polymer nuclei occurs inside the droplets, unlike the capillary-flow-induced spread-out of the nuclei along the contact line in sessile drops. Our method of evaporation of the droplet cluster may facilitate studying LLPS in volume-limited environments and have implications for understanding LLPS in biological systems.
dc.description.versionpublisheddeu
dc.identifier.doi10.1016/j.jciso.2023.100101
dc.identifier.ppn1913787923
dc.identifier.urihttps://kops.uni-konstanz.de/handle/123456789/71786
dc.language.isoeng
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectLiquid-liquid phase separation
dc.subjectEvaporation
dc.subjectEmulsion
dc.subjectConfinement
dc.subjectMarangoni flow
dc.subject.ddc530
dc.titleEvaporative phase separation in polymer microdroplets with confinement and internal floweng
dc.typeJOURNAL_ARTICLE
dspace.entity.typePublication
kops.citation.bibtex
@article{Kumar2024-04Evapo-71786,
  year={2024},
  doi={10.1016/j.jciso.2023.100101},
  title={Evaporative phase separation in polymer microdroplets with confinement and internal flow},
  volume={13},
  issn={2666-934X},
  journal={JCIS Open},
  author={Kumar, Mukesh and Gopu, Maheshwar Reddy and Pugalneelam Parameswaran, Senthan and Joshi, Prerak and Mampallil, Dileep},
  note={Article Number: 100101}
}
kops.citation.iso690KUMAR, Mukesh, Maheshwar Reddy GOPU, Senthan PUGALNEELAM PARAMESWARAN, Prerak JOSHI, Dileep MAMPALLIL, 2024. Evaporative phase separation in polymer microdroplets with confinement and internal flow. In: JCIS Open. Elsevier. 2024, 13, 100101. ISSN 2666-934X. Verfügbar unter: doi: 10.1016/j.jciso.2023.100101deu
kops.citation.iso690KUMAR, Mukesh, Maheshwar Reddy GOPU, Senthan PUGALNEELAM PARAMESWARAN, Prerak JOSHI, Dileep MAMPALLIL, 2024. Evaporative phase separation in polymer microdroplets with confinement and internal flow. In: JCIS Open. Elsevier. 2024, 13, 100101. ISSN 2666-934X. Available under: doi: 10.1016/j.jciso.2023.100101eng
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kops.sourcefieldJCIS Open. Elsevier. 2024, <b>13</b>, 100101. ISSN 2666-934X. Verfügbar unter: doi: 10.1016/j.jciso.2023.100101deu
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source.publisherElsevier

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