Synthesis of bacterial 2-alkyl-4(1H)-quinolone derivatives

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Nguyen_2-qpe66r3wpze76.pdf
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2021
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Arkivoc. Arkat. 2021(IX), pp. 218-239. ISSN 1551-7012. eISSN 1551-7004. Available under: doi: 10.24820/ark.5550190.p011.547
Zusammenfassung

The compound class of 2-alkyl-4(1H)-quinolones represents a unique group of bacterial secondary metabolites that have been the subject of extensive research since their first discovery over 70 years ago. New insights into their structural diversity and their role in the complex interactions in bacterial ecology and human pathogenicity are still being discovered. In parallel with the ongoing discovery of new 2-alkyl-4(1H)-quinolones and derivatives produced by microbes, synthetic methods were developed to facilitate access to these structurally diverse bioactive compounds. Here we present a detailed overview of the historical development and recent advances in their chemical synthesis.

Zusammenfassung in einer weiteren Sprache
Fachgebiet (DDC)
540 Chemie
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Quinolones, quorum sensing, AQNOs, Pseudomonas, Burkholderia
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ISO 690BÖTTCHER, Thomas, David SZAMOSVARI, Thi Hong Nhung NGUYEN, 2021. Synthesis of bacterial 2-alkyl-4(1H)-quinolone derivatives. In: Arkivoc. Arkat. 2021(IX), pp. 218-239. ISSN 1551-7012. eISSN 1551-7004. Available under: doi: 10.24820/ark.5550190.p011.547
BibTex
@article{Bottcher2021Synth-56017,
  year={2021},
  doi={10.24820/ark.5550190.p011.547},
  title={Synthesis of bacterial 2-alkyl-4(1H)-quinolone derivatives},
  number={IX},
  issn={1551-7012},
  journal={Arkivoc},
  pages={218--239},
  author={Böttcher, Thomas and Szamosvari, David and Nguyen, Thi Hong Nhung}
}
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