Synthesis of bacterial 2-alkyl-4(1H)-quinolone derivatives

Böttcher, Thomas; Szamosvari, David; Nguyen, Thi Hong Nhung

Synthesis of bacterial 2-alkyl-4(1H)-quinolone derivatives

Dateien

Nguyen_2-qpe66r3wpze76.pdfGröße: 1.39 MBDownloads: 178

Datum

2021

Publikationstyp

Zeitschriftenartikel

Publikationsstatus

Published

Erschienen in

Arkivoc. Arkat. 2021(IX), pp. 218-239. ISSN 1551-7012. eISSN 1551-7004. Available under: doi: 10.24820/ark.5550190.p011.547

Zusammenfassung

The compound class of 2-alkyl-4(1H)-quinolones represents a unique group of bacterial secondary metabolites that have been the subject of extensive research since their first discovery over 70 years ago. New insights into their structural diversity and their role in the complex interactions in bacterial ecology and human pathogenicity are still being discovered. In parallel with the ongoing discovery of new 2-alkyl-4(1H)-quinolones and derivatives produced by microbes, synthetic methods were developed to facilitate access to these structurally diverse bioactive compounds. Here we present a detailed overview of the historical development and recent advances in their chemical synthesis.

Fachgebiet (DDC)

540 Chemie

Schlagwörter

Quinolones, quorum sensing, AQNOs, Pseudomonas, Burkholderia

Zitieren

ISO 690

BÖTTCHER, Thomas, David SZAMOSVARI, Thi Hong Nhung NGUYEN, 2021. Synthesis of bacterial 2-alkyl-4(1H)-quinolone derivatives. In: Arkivoc. Arkat. 2021(IX), pp. 218-239. ISSN 1551-7012. eISSN 1551-7004. Available under: doi: 10.24820/ark.5550190.p011.547

BibTex

@article{Bottcher2021Synth-56017,
  year={2021},
  doi={10.24820/ark.5550190.p011.547},
  title={Synthesis of bacterial 2-alkyl-4(1H)-quinolone derivatives},
  number={IX},
  issn={1551-7012},
  journal={Arkivoc},
  pages={218--239},
  author={Böttcher, Thomas and Szamosvari, David and Nguyen, Thi Hong Nhung}
}

RDF

<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/56017">
    <dc:creator>Szamosvari, David</dc:creator>
    <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/56017"/>
    <dc:rights>terms-of-use</dc:rights>
    <dcterms:title>Synthesis of bacterial 2-alkyl-4(1H)-quinolone derivatives</dcterms:title>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/29"/>
    <dc:contributor>Nguyen, Thi Hong Nhung</dc:contributor>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2021-12-23T09:05:13Z</dcterms:available>
    <dcterms:issued>2021</dcterms:issued>
    <dc:language>eng</dc:language>
    <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/56017/1/Nguyen_2-qpe66r3wpze76.pdf"/>
    <dc:contributor>Böttcher, Thomas</dc:contributor>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2021-12-23T09:05:13Z</dc:date>
    <dc:contributor>Szamosvari, David</dc:contributor>
    <dc:creator>Böttcher, Thomas</dc:creator>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/29"/>
    <dc:creator>Nguyen, Thi Hong Nhung</dc:creator>
    <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/56017/1/Nguyen_2-qpe66r3wpze76.pdf"/>
    <dcterms:abstract xml:lang="eng">The compound class of 2-alkyl-4(1H)-quinolones represents a unique group of bacterial secondary metabolites that have been the subject of extensive research since their first discovery over 70 years ago. New insights into their structural diversity and their role in the complex interactions in bacterial ecology and human pathogenicity are still being discovered. In parallel with the ongoing discovery of new 2-alkyl-4(1H)-quinolones and derivatives produced by microbes, synthetic methods were developed to facilitate access to these structurally diverse bioactive compounds. Here we present a detailed overview of the historical development and recent advances in their chemical synthesis.</dcterms:abstract>
    <dcterms:rights rdf:resource="https://rightsstatements.org/page/InC/1.0/"/>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
  </rdf:Description>
</rdf:RDF>

Universitätsbibliographie

Ja

Begutachtet

Ja