@article{Summerer2005-07-25Enhan-452,
  year={2005},
  doi={10.1002/anie.200500047},
  title={Enhanced fidelity in mismatch extension by DNA polymerase through directed combinatorial enzyme design},
  number={30},
  volume={44},
  issn={1433-7851},
  journal={Angewandte Chemie International Edition},
  pages={4712--4715},
  author={Summerer, Daniel and Rudinger, Nicolas Z. and Detmer, Ilka and Marx, Andreas}
}

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    <dcterms:bibliographicCitation>First publ. in: Angewandte Chemie International Edition 44 (2005), 30, pp. 4712-4715</dcterms:bibliographicCitation>
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    <dcterms:abstract xml:lang="eng">How is a selective enzyme made even more selective? With a combinatorial approach to redesign an enzyme motif the mismatch extension selectivity of DNA polymerases was increased. The results impart new and deeper insight into the mechanisms of DNA polymerases and provide new tools for applications such as efficient genotyping.</dcterms:abstract>
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