Publikation: Neuroendocrine Mechanisms of Stress Regulation in Humans
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Stress research has made profound discoveries over the past few years. In line with the notion that the acute stress response aims at re-establishing an equilibrium that was disturbed by the stressful agent, the various stress systems in the human body interact, being directed by specific brain structures and systems. The interplay between these systems regulating the stress response in the human are complex and we are only beginning to understand their interaction and their net effect on the regulation of the stress response. Various brain systems are either inhibitory or excitatory to the activation of the stress systems and can change their role depending on the amount of circulating glucocorticoids and the status of the perceived threat. New assessment and manipulation methods now allow a better understanding of the function of these various systems, and their interaction, when it comes to the processing of stress in humans. In this chapter, some of the basics of these systems and structures are first reviewed before discussing some recent developments, which the authors believe have the possibility to allow for refined experimental stress designs in the future.
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PRUESSNER, Jens C., Nida ALI, 2015. Neuroendocrine Mechanisms of Stress Regulation in Humans. In: RUSSELL, John, ed., Michael SHIPSTON, ed.. Neuroendocrinology of Stress. Chichester, UK: Wiley Blackwell, 2015, pp. 121-142. ISBN 978-1-119-95170-4. Available under: doi: 10.1002/9781118921692.ch6BibTex
@incollection{Pruessner2015-09-15Neuro-38517,
year={2015},
doi={10.1002/9781118921692.ch6},
title={Neuroendocrine Mechanisms of Stress Regulation in Humans},
isbn={978-1-119-95170-4},
publisher={Wiley Blackwell},
address={Chichester, UK},
booktitle={Neuroendocrinology of Stress},
pages={121--142},
editor={Russell, John and Shipston, Michael},
author={Pruessner, Jens C. and Ali, Nida}
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<dcterms:abstract xml:lang="eng">Stress research has made profound discoveries over the past few years. In line with the notion that the acute stress response aims at re-establishing an equilibrium that was disturbed by the stressful agent, the various stress systems in the human body interact, being directed by specific brain structures and systems. The interplay between these systems regulating the stress response in the human are complex and we are only beginning to understand their interaction and their net effect on the regulation of the stress response. Various brain systems are either inhibitory or excitatory to the activation of the stress systems and can change their role depending on the amount of circulating glucocorticoids and the status of the perceived threat. New assessment and manipulation methods now allow a better understanding of the function of these various systems, and their interaction, when it comes to the processing of stress in humans. In this chapter, some of the basics of these systems and structures are first reviewed before discussing some recent developments, which the authors believe have the possibility to allow for refined experimental stress designs in the future.</dcterms:abstract>
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