@inproceedings{Richter2012-05Skele-22432,
  year={2012},
  doi={10.1109/ISBI.2012.6235762},
  title={Skeleton-based gyri sulci separation for improved assessment of cortical thickness},
  isbn={978-1-4577-1857-1},
  publisher={IEEE},
  booktitle={2012 9th IEEE International Symposium on Biomedical Imaging (ISBI)},
  pages={1144--1147},
  author={Richter, Mirco and Bishop, Courtney A. and Dukart, Jürgen and Stühler, Elisabeth and Müller, Karsten and Schroeter, Matthias L. and Merhof, Dorit}
}

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    <dc:contributor>Merhof, Dorit</dc:contributor>
    <dc:contributor>Dukart, Jürgen</dc:contributor>
    <dc:creator>Müller, Karsten</dc:creator>
    <dc:language>eng</dc:language>
    <dcterms:issued>2012-05</dcterms:issued>
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    <dc:contributor>Schroeter, Matthias L.</dc:contributor>
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    <dc:creator>Schroeter, Matthias L.</dc:creator>
    <dcterms:bibliographicCitation>9th IEEE International Symposium on Biomedical Imaging (ISBI 2012) : Barcelona, Spain, 2 - 5 May 2012 / [IEEE Signal Processing Society (SPS) and the IEEE Engineering in Medicine and Biology Society (EMBS)]. - Piscataway, NJ : IEEE, 2012. - S. 1144-1147. - ISBN 978-1-4577-1857-1</dcterms:bibliographicCitation>
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    <dc:creator>Stühler, Elisabeth</dc:creator>
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    <dc:creator>Bishop, Courtney A.</dc:creator>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2013-03-19T14:06:11Z</dc:date>
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    <dc:contributor>Müller, Karsten</dc:contributor>
    <dcterms:title>Skeleton-based gyri sulci separation for improved assessment of cortical thickness</dcterms:title>
    <dc:creator>Richter, Mirco</dc:creator>
    <dcterms:abstract xml:lang="eng">In order to improve classification of neurological diseases involving cortical thinning, this work proposes an approach for separating gyral and sulcal regions of the human cortex. Using data from magnetic resonance imaging, the skeleton of the brain's white matter was reconstructed and a geodesic distance measure was applied to separate gyri and sulci. Cortical thickness per subregion was measured for the entire cortex and for gyri and sulci individually in 21 patients with Alzheimer's disease, 10 patients with frontotemporal lobar degeneration composed of two subgroups and 13 control subjects. For discrimination using logistic regressions, which was assessed using leave-one-out cross-validation, improved results were obtained in five out of six group comparisons when cortical thickness measurements were constrained to gyral or sulcal regions.</dcterms:abstract>
    <dc:contributor>Stühler, Elisabeth</dc:contributor>
    <dc:creator>Dukart, Jürgen</dc:creator>
    <dc:creator>Merhof, Dorit</dc:creator>
    <dc:contributor>Richter, Mirco</dc:contributor>
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    <dc:contributor>Bishop, Courtney A.</dc:contributor>
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