Interactions of non-polar and "click-able" nucleotides in the confines of a DNA polymerase active site

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Chemical Communications. 2012, 48(67), pp. 8320-8322. ISSN 1359-7345. eISSN 1364-548X. Available under: doi: 10.1039/C2CC34181F
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Modified nucleotides play a paramount role in many cuttingedge biomolecular techniques. The present structural study highlights the plasticity and flexibility of the active site of a DNA polymerase while incorporating non-polar "Click-able" nucleotide analogs and emphasizes new insights into rational design guidelines for modified nucleotides.

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ISO 690LUDMANN, Samra, Holger BUSSKAMP, Wolfram WELTE, Kay DIEDERICHS, Andreas MARX, 2012. Interactions of non-polar and "click-able" nucleotides in the confines of a DNA polymerase active site. In: Chemical Communications. 2012, 48(67), pp. 8320-8322. ISSN 1359-7345. eISSN 1364-548X. Available under: doi: 10.1039/C2CC34181F
BibTex
@article{Ludmann2012-08-28Inter-20494,
  year={2012},
  doi={10.1039/C2CC34181F},
  title={Interactions of non-polar and "click-able" nucleotides in the confines of a DNA polymerase active site},
  number={67},
  volume={48},
  issn={1359-7345},
  journal={Chemical Communications},
  pages={8320--8322},
  author={Ludmann, Samra and Bußkamp, Holger and Welte, Wolfram and Diederichs, Kay and Marx, Andreas}
}
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