The Systems Biology Graphical Notation

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2009
Autor:innen
Novère, Nicolas Le
Hucka, Michael
Mi, Huaiyu
Moodie, Stuart
Sorokin, Anatoly
Demir, Emek
Wegner, Katja
Aladjem, Mirit I.
Wimalaratne, Sarala M.
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Nature Biotechnology. Springer Science and Business Media LLC. 2009, 27(8), pp. 735-741. ISSN 1087-0156. eISSN 1546-1696. Available under: doi: 10.1038/nbt.1558
Zusammenfassung

Circuit diagrams and Unified Modeling Language diagrams are just two examples of standard visual languages that help accelerate work by promoting regularity, removing ambiguity and enabling software tool support for communication of complex information. Ironically, despite having one of the highest ratios of graphical to textual information, biology still lacks standard graphical notations. The recent deluge of biological knowledge makes addressing this deficit a pressing concern. Toward this goal, we present the Systems Biology Graphical Notation (SBGN), a visual language developed by a community of biochemists, modelers and computer scientists. SBGN consists of three complementary languages: process diagram, entity relationship diagram and activity flow diagram. Together they enable scientists to represent networks of biochemical interactions in a standard, unambiguous way. We believe that SBGN will foster efficient and accurate representation, visualization, storage, exchange and reuse of information on all kinds of biological knowledge, from gene regulation, to metabolism, to cellular signaling.

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ISO 690NOVÈRE, Nicolas Le, Michael HUCKA, Huaiyu MI, Stuart MOODIE, Falk SCHREIBER, Anatoly SOROKIN, Emek DEMIR, Katja WEGNER, Mirit I. ALADJEM, Sarala M. WIMALARATNE, 2009. The Systems Biology Graphical Notation. In: Nature Biotechnology. Springer Science and Business Media LLC. 2009, 27(8), pp. 735-741. ISSN 1087-0156. eISSN 1546-1696. Available under: doi: 10.1038/nbt.1558
BibTex
@article{Novere2009-08Syste-70046,
  year={2009},
  doi={10.1038/nbt.1558},
  title={The Systems Biology Graphical Notation},
  number={8},
  volume={27},
  issn={1087-0156},
  journal={Nature Biotechnology},
  pages={735--741},
  author={Novère, Nicolas Le and Hucka, Michael and Mi, Huaiyu and Moodie, Stuart and Schreiber, Falk and Sorokin, Anatoly and Demir, Emek and Wegner, Katja and Aladjem, Mirit I. and Wimalaratne, Sarala M.}
}
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