The Current Status and Work of Three Rs Centres and Platforms in Europe

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2022
Autor:innen
Neuhaus, Winfried
Reininger-Gutmann, Birgit
Rinner, Beate
Plasenzotti, Roberto
Wilflingseder, Doris
De Kock, Joery
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TOX-Free Toxicity assessment on neurons and cardiomyocytes by means of FluoRescence Emitting Electrodes
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Alternatives to Laboratory Animals : ATLA. Sage. 2022, 50(6), pp. 381-413. ISSN 0261-1929. eISSN 2632-3559. Available under: doi: 10.1177/02611929221140909
Zusammenfassung

The adoption of Directive 2010/63/EU on the protection of animals used for scientific purposes has given a major push to the formation of Three Rs initiatives in the form of centres and platforms. These centres and platforms are dedicated to the so-called Three Rs, which are the Replacement, Reduction and Refinement of animal use in experiments. ATLA's 50th Anniversary year has seen the publication of two articles on European Three Rs centres and platforms. The first of these was about the progressive rise in their numbers and about their founding history; this second part focuses on their current status and activities. This article takes a closer look at their financial and organisational structures, describes their Three Rs focus and core activities (dissemination, education, implementation, scientific quality/translatability, ethics), and presents their areas of responsibility and projects in detail. This overview of the work and diverse structures of the Three Rs centres and platforms is not only intended to bring them closer to the reader, but also to provide role models and show examples of how such Three Rs centres and platforms could be made sustainable. The Three Rs centres and platforms are very important focal points and play an immense role as facilitators of Directive 2010/63/EU 'on the ground' in their respective countries. They are also invaluable for the wide dissemination of information and for promoting the implementation of the Three Rs in general.

Zusammenfassung in einer weiteren Sprache
Fachgebiet (DDC)
570 Biowissenschaften, Biologie
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3R, 3Rs, EU3Rnet, NAM, NAMs, new approach methodologies, novel approach methodologies, non-animal methods
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ISO 690NEUHAUS, Winfried, Birgit REININGER-GUTMANN, Beate RINNER, Roberto PLASENZOTTI, Doris WILFLINGSEDER, Joery DE KOCK, Thomas HARTUNG, Giorgia PALLOCCA, Costanza ROVIDA, Marcel LEIST, 2022. The Current Status and Work of Three Rs Centres and Platforms in Europe. In: Alternatives to Laboratory Animals : ATLA. Sage. 2022, 50(6), pp. 381-413. ISSN 0261-1929. eISSN 2632-3559. Available under: doi: 10.1177/02611929221140909
BibTex
@article{Neuhaus2022-11Curre-59426,
  year={2022},
  doi={10.1177/02611929221140909},
  title={The Current Status and Work of Three Rs Centres and Platforms in Europe},
  number={6},
  volume={50},
  issn={0261-1929},
  journal={Alternatives to Laboratory Animals : ATLA},
  pages={381--413},
  author={Neuhaus, Winfried and Reininger-Gutmann, Birgit and Rinner, Beate and Plasenzotti, Roberto and Wilflingseder, Doris and De Kock, Joery and Hartung, Thomas and Pallocca, Giorgia and Rovida, Costanza and Leist, Marcel}
}
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