Publikation: Biomimetic Growth of Calcium Oxalate Hydrates : Shape Development and Structures in Agar Gel Matrices
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2025
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Chemistry – A European Journal. Wiley. 2025, 31(25), e202404269. ISSN 0947-6539. eISSN 1521-3765. Verfügbar unter: doi: 10.1002/chem.202404269
Zusammenfassung
Crystal growth of calcium oxalate hydrates (COM: calcium oxalate monohydrate; COD: ‐dihydrate; COT: ‐trihydrate) is a specific example of biomineralization due to their harmful role as kidney/urinary stones. In this work, the biomimetic growth of calcium oxalate hydrates has been achieved using double diffusion technique in agar gel matrix. In‐vitro experimental models for the growth of calcium oxalates can give valuable information on the formation of kidney/urinary stones. Diverse morphological forms of COM are grown in agar gel matrices ranging from platy crystallites to dumbbells and spherulites. The morphology of COM grown in agar gel resembles biogenic COM stones remarkably. Furthermore, it has been discovered that a higher pH of the agar gel promotes COD development while suppressing COM growth.
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Fachgebiet (DDC)
540 Chemie
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Biomimetic synthesis, agar gel, calcium oxalates, double diffusion, morphology
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THOMAS, Annu, Paul SIMON, Wilder CARRILLO-CABRERA, Elena V. STURM, 2025. Biomimetic Growth of Calcium Oxalate Hydrates : Shape Development and Structures in Agar Gel Matrices. In: Chemistry – A European Journal. Wiley. 2025, 31(25), e202404269. ISSN 0947-6539. eISSN 1521-3765. Verfügbar unter: doi: 10.1002/chem.202404269BibTex
@article{Thomas2025-05Biomi-72915,
title={Biomimetic Growth of Calcium Oxalate Hydrates : Shape Development and Structures in Agar Gel Matrices},
year={2025},
doi={10.1002/chem.202404269},
number={25},
volume={31},
issn={0947-6539},
journal={Chemistry – A European Journal},
author={Thomas, Annu and Simon, Paul and Carrillo-Cabrera, Wilder and Sturm, Elena V.},
note={Article Number: e202404269}
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<dcterms:abstract>Crystal growth of calcium oxalate hydrates (COM: calcium oxalate monohydrate; COD: ‐dihydrate; COT: ‐trihydrate) is a specific example of biomineralization due to their harmful role as kidney/urinary stones. In this work, the biomimetic growth of calcium oxalate hydrates has been achieved using double diffusion technique in agar gel matrix. In‐vitro experimental models for the growth of calcium oxalates can give valuable information on the formation of kidney/urinary stones. Diverse morphological forms of COM are grown in agar gel matrices ranging from platy crystallites to dumbbells and spherulites. The morphology of COM grown in agar gel resembles biogenic COM stones remarkably. Furthermore, it has been discovered that a higher pH of the agar gel promotes COD development while suppressing COM growth.</dcterms:abstract>
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