How reggies regulate regeneration and axon growth

Stürmer, Claudia

How reggies regulate regeneration and axon growth

Dateien

how_reggies_regulate.pdfGröße: 5.35 MBDownloads: 544

Datum

2012

Open Access-Veröffentlichung

Open Access Green

Sammlungen

Biologie

Publikationstyp

Zeitschriftenartikel

Publikationsstatus

Published

Erschienen in

Cell and Tissue Research. 2012, 349(1), pp. 71-77. ISSN 0302-766X. eISSN 1432-0878. Available under: doi: 10.1007/s00441-012-1343-6

Zusammenfassung

The microdomain-forming proteins reggie-1 and reggie-2 (alias flotillins) were found to be upregulated in axon-regenerating fish retinal ganglion cells (RGCs). They were subsequently shown to be indispensible for axon regeneration and neurite extension in fish and mammals. Our current concept proposes that reggies-often together with the cellular Prion protein (PrP)-regulate the turnover of membrane and specific membrane proteins at the growth cone, which is the prerequisite for neurite elongation and guidance.

Fachgebiet (DDC)

570 Biowissenschaften, Biologie

Zitieren

ISO 690

STÜRMER, Claudia, 2012. How reggies regulate regeneration and axon growth. In: Cell and Tissue Research. 2012, 349(1), pp. 71-77. ISSN 0302-766X. eISSN 1432-0878. Available under: doi: 10.1007/s00441-012-1343-6

BibTex

@article{Sturmer2012-07reggi-19176,
  year={2012},
  doi={10.1007/s00441-012-1343-6},
  title={How reggies regulate regeneration and axon growth},
  number={1},
  volume={349},
  issn={0302-766X},
  journal={Cell and Tissue Research},
  pages={71--77},
  author={Stürmer, Claudia}
}

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Universitätsbibliographie

Ja