Publikation:

Fast and Reliable Quantitative Peptidomics with labelpepmatch

Vorschaubild

Dateien

Zu diesem Dokument gibt es keine Dateien.

Datum

2016

Autor:innen

Verdonck, Rik
De Haes, Wouter
Cardoen, Dries
Menschaert, Gerben
Landuyt, Bart
Baggerman, Geert
Boonen, Kurt
Wenseleers, Tom
Schoofs, Liliane

Herausgeber:innen

Kontakt

ISSN der Zeitschrift

Electronic ISSN

ISBN

Bibliografische Daten

Verlag

Schriftenreihe

Auflagebezeichnung

URI (zitierfähiger Link)
DOI (zitierfähiger Link)
https://doi.org/10.1021/acs.jproteome.5b00845
ArXiv-ID

Internationale Patentnummer

Angaben zur Forschungsförderung

Projekt

Open Access-Veröffentlichung

Sammlungen

Chemie: Publikationen
Core Facility der Universität Konstanz

Gesperrt bis

Titel in einer weiteren Sprache

Publikationstyp
Zeitschriftenartikel
Publikationsstatus
Published

Erschienen in

Journal of Proteome Research. 2016, 15(3), pp. 1080-1089. ISSN 1535-3893. eISSN 1535-3907. Available under: doi: 10.1021/acs.jproteome.5b00845

Zusammenfassung

The use of stable isotope tags in quantitative peptidomics offers many advantages, but the laborious identification of matching sets of labeled peptide peaks is still a major bottleneck. Here we present labelpepmatch, an R-package for fast and straightforward analysis of LC-MS spectra of labeled peptides. This open-source tool offers fast and accurate identification of peak pairs alongside an appropriate framework for statistical inference on quantitative peptidomics data, based on techniques from other -omics disciplines. A relevant case study on the desert locust Schistocerca gregaria proves our pipeline to be a reliable tool for quick but thorough explorative analyses.

Zusammenfassung in einer weiteren Sprache

Fachgebiet (DDC)
540 Chemie

Schlagwörter

Konferenz

Rezension
undefined / . - undefined, undefined

Forschungsvorhaben

Organisationseinheiten

Zeitschriftenheft

Zugehörige Datensätze in KOPS

Zitieren

ISO 690VERDONCK, Rik, Wouter DE HAES, Dries CARDOEN, Gerben MENSCHAERT, Thomas HUHN, Bart LANDUYT, Geert BAGGERMAN, Kurt BOONEN, Tom WENSELEERS, Liliane SCHOOFS, 2016. Fast and Reliable Quantitative Peptidomics with labelpepmatch. In: Journal of Proteome Research. 2016, 15(3), pp. 1080-1089. ISSN 1535-3893. eISSN 1535-3907. Available under: doi: 10.1021/acs.jproteome.5b00845
BibTex
@article{Verdonck2016-03-04Relia-33667,
  year={2016},
  doi={10.1021/acs.jproteome.5b00845},
  title={Fast and Reliable Quantitative Peptidomics with labelpepmatch},
  number={3},
  volume={15},
  issn={1535-3893},
  journal={Journal of Proteome Research},
  pages={1080--1089},
  author={Verdonck, Rik and De Haes, Wouter and Cardoen, Dries and Menschaert, Gerben and Huhn, Thomas and Landuyt, Bart and Baggerman, Geert and Boonen, Kurt and Wenseleers, Tom and Schoofs, Liliane}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/33667">
    <dc:contributor>Cardoen, Dries</dc:contributor>
    <dcterms:issued>2016-03-04</dcterms:issued>
    <dc:contributor>Menschaert, Gerben</dc:contributor>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/33667"/>
    <dc:creator>Baggerman, Geert</dc:creator>
    <dc:contributor>Wenseleers, Tom</dc:contributor>
    <dc:creator>Boonen, Kurt</dc:creator>
    <dc:creator>Verdonck, Rik</dc:creator>
    <dc:creator>De Haes, Wouter</dc:creator>
    <dc:contributor>Baggerman, Geert</dc:contributor>
    <dc:contributor>Verdonck, Rik</dc:contributor>
    <dc:contributor>Boonen, Kurt</dc:contributor>
    <dcterms:abstract xml:lang="eng">The use of stable isotope tags in quantitative peptidomics offers many advantages, but the laborious identification of matching sets of labeled peptide peaks is still a major bottleneck. Here we present labelpepmatch, an R-package for fast and straightforward analysis of LC-MS spectra of labeled peptides. This open-source tool offers fast and accurate identification of peak pairs alongside an appropriate framework for statistical inference on quantitative peptidomics data, based on techniques from other -omics disciplines. A relevant case study on the desert locust Schistocerca gregaria proves our pipeline to be a reliable tool for quick but thorough explorative analyses.</dcterms:abstract>
    <dc:creator>Huhn, Thomas</dc:creator>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/29"/>
    <dc:language>eng</dc:language>
    <dc:contributor>Landuyt, Bart</dc:contributor>
    <dc:creator>Schoofs, Liliane</dc:creator>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <dc:creator>Cardoen, Dries</dc:creator>
    <dc:contributor>Schoofs, Liliane</dc:contributor>
    <dc:contributor>Huhn, Thomas</dc:contributor>
    <dcterms:title>Fast and Reliable Quantitative Peptidomics with labelpepmatch</dcterms:title>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2016-04-22T12:01:09Z</dc:date>
    <dc:contributor>De Haes, Wouter</dc:contributor>
    <dc:creator>Wenseleers, Tom</dc:creator>
    <dc:creator>Landuyt, Bart</dc:creator>
    <dc:creator>Menschaert, Gerben</dc:creator>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2016-04-22T12:01:09Z</dcterms:available>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/29"/>
  </rdf:Description>
</rdf:RDF>

Interner Vermerk

xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter

Kontakt
URL der Originalveröffentl.

Prüfdatum der URL

Prüfungsdatum der Dissertation

Finanzierungsart

Kommentar zur Publikation

Allianzlizenz
Corresponding Authors der Uni Konstanz vorhanden
Internationale Co-Autor:innen
Universitätsbibliographie
Ja
Begutachtet
Diese Publikation teilen